Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.5.1.2
Substance Class Protein
Protein Type ENZYME
Protein Sub Type TYROSINE KINASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
RSO83C9PIA
Record Status Validated (UNII)
Record Version
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Name Type Language Details References
RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3
Common Name
English  
PROTO-ONCOGENE-LIKE PROTEIN C-ERBB-3
Common Name
English  
HER3
Common Name
English  
ERBB3
Common Name
English  
TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER3
Common Name
English  
Code System Code Type Description References
PHAROS
P21860
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
PRIMARY
UNIPROT
P21860
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
PRIMARY
From To
1_10 1_37
1_137 1_164
1_167 1_175
1_171 1_183
1_191 1_199
1_195 1_207
1_208 1_216
1_212 1_224
1_227 1_236
1_240 1_267
1_271 1_282
1_286 1_301
1_304 1_308
1_481 1_490
1_485 1_498
1_501 1_510
1_514 1_530
1_533 1_546
1_537 1_554
1_557 1_566
1_570 1_591
1_594 1_602
1_598 1_610
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_107
N 1_231
N 1_334
N 1_389
N 1_395
N 1_418
N 1_450
N 1_503
N 1_547
N 1_597
Related Record Type Details References
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
Mediator Substance Details
none
IgG1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity targeting HER2 and HER3 receptors.
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Fri Jul 10 19:51:57 EDT 2020 , Edited by admin on Fri Jul 10 19:51:57 EDT 2020
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
AMINO ACID SUBSTITUTION [1_667] [1_963] DEXFOSFOSERINE VI4F0K069V
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL 0
Created Fri Jul 10 19:51:57 EDT 2020
Created By admin
Last Edited Fri Jul 10 19:51:57 EDT 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-erbb3-monoclonal-antibody-regn1400 NCI DRUG DICTIONARY NOMEN PUBLIC_DOMAIN_RELEASE
2 http://www.uniprot.org/uniprot/P21860 SRS NOMEN PUBLIC_DOMAIN_RELEASE
3 http://www.uniprot.org/uniprot/P21860?sort=score SRS NOMEN
4 UNIPROT UNIPROT NOMEN
5 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:30:25 EDT 2017
6 dump-public-2020-07-07.gsrs BATCH_IMPORT Fri Jul 10 19:51:56 EDT 2020