Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.6.1
Substance Class Protein
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3XPI7EG4W8
Record Status Validated
Record Version
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Name Type Language Details References
PATRITUMAB DERUXTECAN
Domain Jurisdiction Naming Organization
drug  
INN  
Official Name
English  
U3-1402
Code
English  
ANTI-HER3 ANTIBODY-DRUG CONJUGATE U3 1402
Common Name
English  
PATRITUMAB DERUXTECAN [INN]
Common Name
English  
U3-1402A
Code
English  
U3 1402 [WHO-DD]
Common Name
English  
U3 1402
Code
English  
Code System Code Type Description References
INN
11093
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
PRIMARY
CAS
2227102-46-5
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
PRIMARY
FDA UNII
3XPI7EG4W8
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
PRIMARY
NCI_THESAURUS
C136987
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
PRIMARY
From To
1_22 1_95
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_95
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_52
N 1_297
N 2_52
N 2_297
Related Record Type Details References
PARENT -> DERIVATIVE
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
Related Record Type Details References
METABOLITE ACTIVE -> PARENT
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
Related Record Type Details References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 20:33:44 EST 2020 , Edited by admin on Thu Nov 12 20:33:44 EST 2020
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
AMINO_ACID_SUBSTITUTION [1_220] [1_226] [1_229] [2_220] [2_226] [2_229] [3_220] [4_220] SITE_SPECIFIC CYSTEINYL DERUXTECAN I1NS1DHT5R
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL 0
Note References
[Validation]WARNING:There are 4 substances with a similar sequence to subunit [3,4]:
(Perform similarity search on subunit [3])
found approximate duplicate (95%) sequence in Subunit [3] of "6XG22YQM2Z" ("TIRAGOLUMAB")
found approximate duplicate (95%) sequence in Subunit [4] of "6XG22YQM2Z" ("TIRAGOLUMAB")
found approximate duplicate (95%) sequence in Subunit [4] of "UY9LQ8P6HW" ("ODESIVIMAB")
found approximate duplicate (95%) sequence in Subunit [3] of "UY9LQ8P6HW" ("ODESIVIMAB")
Created Thu Nov 12 20:33:44 EST 2020
Created By admin
Last Edited Thu Nov 12 20:33:44 EST 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 SYSTEM
2 INN Proposed List 121 INN_LIST PUBLIC_DOMAIN_RELEASE
3 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 20:33:44 EST 2020
4 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 20:33:44 EST 2020
5 who WHO DRUG DICTIONARY NOMEN PUBLIC_DOMAIN_RELEASE
6 STN STN (SCIFINDER) NOMEN PUBLIC_DOMAIN_RELEASE
7 Anti-HER3 Antibody-drug Conjugate U3 1402 (Code C136987) NCI THESAURUS PUBLIC_DOMAIN_RELEASE