Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.6.1
Substance Class Protein
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
27TW751DTH
Record Status Validated
Record Version
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Name Type Language Details References
ASTEGOLIMAB
Domain Jurisdiction Naming Organization
drug  
USAN   INN  
Official Name
English  
MSTT1041A
Code
English  
IMMUNOGLOBULIN G2, ANTI-(HUMAN INTERLEUKIN-33 RECEPTOR) (HUMAN MONOCLONAL MSTT1041A .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MSTT1041A .KAPPA.-CHAIN, DIMER
Common Name
English  
RG6149
Code
English  
ASTEGOLIMAB [WHO-DD]
Common Name
English  
AMG282
Code
English  
AMG-282
Code
English  
RG-6149
Code
English  
MSTT-1041A
Code
English  
IMMUNOGLOBULIN GX-KAPPA, ANTI-(HOMO SAPIENS INTERLEUKIN-1 RECEPTOR-LIKE 1 (PROTEIN ST2, EC=3.2.2.6)) HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.2 HEAVY CHAIN HOMO SAPIENS (1-447) (HOMO SAPIENS VH (IGHV5-51*01 (96%) (IGHD)-IGHJ6*01 (94%)) (8.8.14) (1-121)-HOM
Common Name
English  
RO-7187807
Code
English  
ASTEGOLIMAB [USAN]
Common Name
English  
ASTEGOLIMAB [INN]
Common Name
English  
HUMAN MAB THAT INHIBITS THE BINDING OF IL-33 (NF-HEV) TO IL-1 RECEPTOR-LIKE 1
Common Name
English  
Code System Code Type Description References
INN
11067
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
PRIMARY
CAS
2173054-79-8
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
PRIMARY
NCI_THESAURUS
C171824
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
PRIMARY
FDA UNII
27TW751DTH
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
PRIMARY
From To
1_22 1_96
1_135 3_214
1_148 1_204
1_223 2_223
1_224 2_224
1_227 2_227
1_230 2_230
1_261 1_321
1_367 1_425
2_22 2_96
2_135 4_214
2_148 2_204
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details References
TARGET -> INHIBITOR
none
Mediator Substance Details
none
anti-ST2 human IgG2? monoclonal antibody that blocks IL-33 binding to IL-1 family receptor ST2
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
Related Record Type Details References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 20:18:22 EST 2020 , Edited by admin on Thu Nov 12 20:18:22 EST 2020
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
AMINO ACID REMOVAL C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL 0
Note References
[Validation]WARNING:There are 2 substances with a similar sequence to subunit [3,4]:
(Perform similarity search on subunit [3])
found approximate duplicate (98%) sequence in Subunit [4] of "J0FI6WE1QN" ("CASIRIVIMAB")
found approximate duplicate (98%) sequence in Subunit [3] of "J0FI6WE1QN" ("CASIRIVIMAB")
Created Thu Nov 12 20:18:22 EST 2020
Created By admin
Last Edited Thu Nov 12 20:18:22 EST 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 https://www.gene.com/medical-professionals/pipeline MANUFACTURER PRODUCT DESCRIPTION PUBLIC_DOMAIN_RELEASE
2 https://adisinsight.springer.com/drugs/800047994 WEB PAGE
3 NCIT NCI THESAURUS
4 http://bciq.biocentury.com/products/amg_282 WEB PAGE PUBLIC_DOMAIN_RELEASE
5 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 20:18:22 EST 2020
6 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 20:18:22 EST 2020
7 WHO-DD WHO DRUG DICTIONARY
8 SCIFINDER STN (SCIFINDER)
9 INN Proposed List 121 INN_LIST PUBLIC_DOMAIN_RELEASE
10 USAN COUN 2020 USANCOUN PUBLIC_DOMAIN_RELEASE NOMEN