Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.6.1
Substance Class Protein
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
06P3KLK2J8
Record Status Validated
Record Version
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Name Type Language Details References
GLOFITAMAB
Domain Jurisdiction Naming Organization
drug  
INN   USAN  
Official Name
English  
IMMUNOGLOBULIN G1 (149-GLUTAMIC ACID,215-GLUTAMIC ACID,461-ALANINE,462-ALANINE,556-GLYCINE,581-CYSTEINE,593-TRYPTOPHAN), ANTI-(HUMAN CD20 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL RG6026 VH-CH1 FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 10-AMINO ACID
Common Name
English  
GLOFITAMAB [INN]
Common Name
English  
RG-6026
Code
English  
GLOFITAMAB [USAN]
Common Name
English  
ANTI-CD20/CD3 BISPECIFIC MONOCLONAL ANTIBODY RO7082859
Common Name
English  
RO7082859
Code
English  
RO-7082859
Code
English  
IMMUNOGLOBULIN G1-LAMBDA/KAPPA WITH DOMAIN CROSS-OVER, ANTI-(HOMO SAPIENS MS4A1 (MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 1, CD20)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)) MONOCLONAL ANTIBODY, BISPECIFIC, TRIVALENTGAMMA-LAMBDA HEAVY CHAIN
Common Name
English  
Code System Code Type Description References
INN
11145
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
PRIMARY
CAS
2229047-91-8
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
PRIMARY
FDA UNII
06P3KLK2J8
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
PRIMARY
NCI_THESAURUS
C148486
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
PRIMARY
From To
1_22 1_96
1_146 1_202
1_255 1_323
1_371 1_427
1_447 5_232
1_453 2_228
1_456 2_231
1_488 1_548
1_222 3_219
1_594 1_652
2_22 2_96
2_146 2_202
2_222 4_219
2_263 2_323
2_369 2_427
1_581 2_351
3_23 3_93
3_139 3_199
4_23 4_93
4_139 4_199
5_22 5_98
5_152 5_212
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_524
N 2_299
Related Record Type Details References
TARGET->LIGAND
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
TARGET -> ACTIVATOR
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
Related Record Type Details References
ACTIVE MOIETY
none
Mediator Substance Details
none
Created by admin on Thu Nov 12 22:39:05 EST 2020 , Edited by admin on Thu Nov 12 22:39:05 EST 2020
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS PIDOLIC ACID SZB83O1W42
AMINO ACID REMOVAL [1_674] [2_449] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL 0
Note References
[Validation]WARNING:There are 2 substances with a similar sequence to subunit [2]:
(Perform similarity search on subunit [2])
found approximate duplicate (98%) sequence in Subunit [2] of "O43472U9X8" ("OBINUTUZUMAB")
found approximate duplicate (98%) sequence in Subunit [1] of "O43472U9X8" ("OBINUTUZUMAB")
[Validation]WARNING:There are 6 substances with a similar sequence to subunit [3,4]:
(Perform similarity search on subunit [3])
found approximate duplicate (95%) sequence in Subunit [4] of "85V55ZLV2Z" ("GATIPOTUZUMAB")
found approximate duplicate (95%) sequence in Subunit [3] of "85V55ZLV2Z" ("GATIPOTUZUMAB")
found approximate duplicate (95%) sequence in Subunit [4] of "87PZ955YRB" ("FROVOCIMAB")
found approximate duplicate (95%) sequence in Subunit [3] of "87PZ955YRB" ("FROVOCIMAB")
found approximate duplicate (99%) sequence in Subunit [3] of "O43472U9X8" ("OBINUTUZUMAB")
found approximate duplicate (99%) sequence in Subunit [4] of "O43472U9X8" ("OBINUTUZUMAB")
Created Thu Nov 12 22:39:05 EST 2020
Created By admin
Last Edited Thu Nov 12 22:39:05 EST 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 INN Proposed List 121 INN_LIST PUBLIC_DOMAIN_RELEASE
2 USAN COUN 2020 USANCOUN PUBLIC_DOMAIN_RELEASE NOMEN
3 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 22:39:03 EST 2020
4 https://adisinsight.springer.com/drugs/800049116 WEB PAGE NOMEN
5 https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C148486 NCI THESAURUS NOMEN PUBLIC_DOMAIN_RELEASE
6 STN STN (SCIFINDER) NOMEN PUBLIC_DOMAIN_RELEASE
7 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Nov 12 22:39:03 EST 2020