Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
QL6A9B13HW
Record Status Validated
Record Version
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Details

Stereochemistry ABSOLUTE
Molecular Formula C167H252N42O55
Molecular Weight 3728.0362
Optical Activity UNSPECIFIED
Defined Stereocenters 30 / 30
E/Z Centers 0
Charge 0
Created by admin on Wed Aug 04 05:54:46 EDT 2021
Edited by admin on Wed Aug 04 05:54:46 EDT 2021
Structure of COTADUTIDE

Systematic Names:

  • None recorded

SMILES

CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC2=CNC=N2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC3=CC=C(O)C=C3)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC5=CNC6=C5C=CC=C6)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(O)=O)C(O)=O

InChI

YEKUUBPJRPXMBM-PTCFZACGSA-N
InChI=1S/C167H252N42O55/c1-13-14-15-16-17-18-19-20-21-22-23-24-31-47-125(219)186-109(165(263)264)53-58-124(218)175-62-35-34-44-102(189-153(251)116(72-131(228)229)201-161(259)122(83-213)206-164(262)137(92(12)215)209-157(255)114(68-94-40-29-26-30-41-94)202-163(261)136(91(11)214)207-127(221)78-181-142(240)105(52-57-123(169)217)190-158(256)119(80-210)203-141(239)100(168)71-97-76-174-84-182-97)146(244)204-120(81-211)159(257)193-108(56-61-130(226)227)148(246)197-112(69-95-48-50-98(216)51-49-95)151(249)195-111(66-86(4)5)150(248)200-118(74-133(232)233)155(253)205-121(82-212)160(258)192-107(55-60-129(224)225)147(245)188-103(45-36-63-176-166(170)171)143(241)184-89(9)139(237)187-104(46-37-64-177-167(172)173)145(243)199-117(73-132(230)231)154(252)198-113(67-93-38-27-25-28-39-93)156(254)208-135(87(6)7)162(260)185-90(10)140(238)194-115(70-96-75-178-101-43-33-32-42-99(96)101)152(250)196-110(65-85(2)3)149(247)191-106(54-59-128(222)223)144(242)183-88(8)138(236)180-77-126(220)179-79-134(234)235/h25-30,32-33,38-43,48-51,75-76,84-92,100,102-122,135-137,178,210-216H,13-24,31,34-37,44-47,52-74,77-83,168H2,1-12H3,(H2,169,217)(H,174,182)(H,175,218)(H,179,220)(H,180,236)(H,181,240)(H,183,242)(H,184,241)(H,185,260)(H,186,219)(H,187,237)(H,188,245)(H,189,251)(H,190,256)(H,191,247)(H,192,258)(H,193,257)(H,194,238)(H,195,249)(H,196,250)(H,197,246)(H,198,252)(H,199,243)(H,200,248)(H,201,259)(H,202,261)(H,203,239)(H,204,244)(H,205,253)(H,206,262)(H,207,221)(H,208,254)(H,209,255)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,263,264)(H4,170,171,176)(H4,172,173,177)/t88-,89-,90-,91+,92+,100-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,135-,136-,137-/m0/s1
Related Record Type
Alternative Definition
Created by admin on Thu Aug 05 06:04:28 EDT 2021 , Edited by admin on Thu Aug 05 06:04:28 EDT 2021
Name Type Language Details Access References
COTADUTIDE
Domain Jurisdiction Naming Organization
drug  
INN  
Official Name
English  
MEDI0382
Code
English  
MEDI-0382
Code
English  
MEDI 0382 [WHO-DD]
Common Name
English  
HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-LYS-(.GAMMA.-GLUPALMITOYL)-SER-GLU-TYR-LEU-ASP-SER-GLU-ARG-ALA-ARG-ASP- PHE-VAL-ALA-TRP-LEU-GLU-ALA-GLY-GLY
Common Name
English  
GLYCINE, L-HISTIDYL-L-SERYL-L-GLUTAMINYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-ASPARTYL-N6-(N-(1-OXOTETRADECYL)-L-.GAMMA.-GLUTAMYL)-L-LYSYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-TYROSYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-ALANYL-L-ARGINYL-L-.ALPHA.-ASPARTYL-L-PHENYLALANYL-L-VALYL-L-ALANYL-L-TRYPTOPHYL-L-LEUCYL-L-.ALPHA.-GLUTAMYL-L-ALANYLGLYCYL-
Systematic Name
English  
DES-PHOSPHONO(K10,E12,E17,R20,A24,E27,A28)GLUCAGONYL-GG: L-HISTIDYL-L-SERYL-L-GLUTAMINYLGLYCYL-L-THREONYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-ASPARTYL-N6-(N-HEXADECANOYL-L-.GAMMA.-GLUTAMYL)-L-LYSYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-TYROSYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-ALANYL-L-ARGINYL-L-.ALPHA.-ASPARTYL-L-PHENYLALANYL-L-VALYL-L-ALANYL-L-TRYPTOPHYL-L-LEUCYL-L-.ALPHA.-GLUTAMYL-L-ALANYLGLYCYLGLYCINE
Systematic Name
English  
COTADUTIDE [USAN]
Common Name
English  
COTADUTIDE [INN]
Common Name
English  
Code System Code Type Description Access References
CAS
1686108-82-6
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
DRUG BANK
DB15194
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
FDA UNII
QL6A9B13HW
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
INN
10888
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
NCI_THESAURUS
C174890
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
PUBCHEM
134694273
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
PRIMARY
Related Record Type Details Access References
TARGET -> AGONIST
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
TARGET -> AGONIST
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 05:54:46 EDT 2021 , Edited by admin on Wed Aug 04 05:54:46 EDT 2021
Note Access References
[Validation]WARNING:Substance may be represented as protein as well. Sequence:[HSQGTFTSDXSEYLDSERARDFVAWLEAGG]
[Validation]WARNING:alternative definition not found NO NAME
Created Wed Aug 04 05:54:46 EDT 2021
Created By admin
Last Edited Wed Aug 04 05:54:46 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 STN STN (SCIFINDER)
2 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 05:54:43 EDT 2021
3 USAN COUN 2017 USANCOUN PUBLIC_DOMAIN_RELEASE NOMEN
4 SYSTEM
5 GSRS System-generated Validation messages VALIDATION_MESSAGE Wed Aug 04 05:54:43 EDT 2021
6 https://clinicaltrials.gov/ct2/show/NCT03235050 CLINICAL_TRIALS.GOV
7 WHO-DD WHO DRUG DICTIONARY
8 PUBCHEM PUBCHEM NOMEN PUBLIC_DOMAIN_RELEASE
9 FDA_SRS STN (SCIFINDER)
10 NCIT NCI THESAURUS
11 System generated SYSTEM
12 INN Proposed List 119 INN_LIST PUBLIC_DOMAIN_RELEASE

Version

Version Comments

Editor

Change Date

25
admin
Thu Aug 05 02:04:28 EDT 2021

Molecular Formula C167H252N42O55
Molecular Weight 3728.0362
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 30 / 30
E/Z Centers 25
Optical Activity UNSPECIFIED