Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Protein
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
XLR461MD3M
Record Status Validated
Record Version
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Name Type Language Details Access References
ISTIRATUMAB
Domain Jurisdiction Naming Organization
drug  
INN   USAN  
Official Name
English  
MM-141
Code
English  
MM-005
Code
English  
ISTIRATUMAB [WHO-DD]
Common Name
English  
ISTIRATUMAB [USAN]
Common Name
English  
ISTIRATUMAB [INN]
Common Name
English  
IMMUNOGLOBULIN G1, ANTI-(HUMAN INSULIN-LIKE GROWTH FACTOR I RECEPTOR/NEUREGULIN RECEPTOR HER3) (HUMAN MONOCLONAL MM-005 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MM-005 LIGHT CHAIN, DIMER
Common Name
English  
Classification Tree Code System Code Access References
FDA ORPHAN DRUG 450314
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
Code System Code Type Description Access References
CAS
1509928-04-4
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
PRIMARY
DRUG BANK
DB15363
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
PRIMARY
FDA UNII
XLR461MD3M
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
PRIMARY
INN
10431
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
PRIMARY
NCI_THESAURUS
C103863
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
PRIMARY
From To
1_22 1_96
2_22 2_96
3_23 3_88
4_23 4_88
3_134 3_194
4_134 4_194
1_149 1_205
2_149 2_205
1_225 3_214
2_225 4_214
1_231 2_231
1_234 2_234
1_266 1_326
2_266 2_326
1_371 1_429
2_371 2_429
1_487 1_561
2_487 2_561
1_632 1_697
2_632 2_697
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details Access References
TARGET -> INHIBITOR
none
Mediator Substance Details
none
BINDING
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
TARGET -> INHIBITOR
none
Mediator Substance Details
none
BINDING
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Sat Jun 26 20:34:47 EDT 2021 , Edited by admin on Sat Jun 26 20:34:47 EDT 2021
Name Property Type Amount Referenced Substance Defining Parameters Access References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
0
Molecular Formula CHEMICAL
0
Note Access References
[Validation]WARNING:Protein has no molecular formula property, defaulting to calculated value of: C8802H13580O2792N2392S58
[Validation]WARNING:There are 2 substances with a similar sequence to subunit [3,4]:
(Perform similarity search on subunit [3])
found approximate duplicate (95%) sequence in Subunit [3] of "105J35OE21" ("ADUCANUMAB")
found approximate duplicate (95%) sequence in Subunit [4] of "105J35OE21" ("ADUCANUMAB")
Created Sat Jun 26 20:34:47 EDT 2021
Created By admin
Last Edited Sat Jun 26 20:34:47 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 STN SRS NOMEN
2 STN STN (SCIFINDER)
3 ISTIRATUMAB [USAN] SRS_LOCATOR
4 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:33:30 EDT 2017
5 USAN COUN 2016 USANCOUN NOMEN PUBLIC_DOMAIN_RELEASE
6 USAN COUN 2016 SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
7 SRS import [XLR461MD3M] SRS NOMEN Fri Apr 28 15:33:30 EDT 2017
8 SYSTEM
9 USAN SRS NOMEN
10 who WHO DRUG DICTIONARY NOMEN PUBLIC_DOMAIN_RELEASE
11 FDA_SRS SRS NOMEN
12 dump-public-2021-06-23_UPDATED.gsrs BATCH_IMPORT Sat Jun 26 20:34:45 EDT 2021
13 INN Proposed List 117 INN_LIST PUBLIC_DOMAIN_RELEASE
14 GSRS System-generated Validation messages VALIDATION_MESSAGE Sat Jun 26 20:34:47 EDT 2021