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Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
Query Builder
version 2.7.1
Substance Class Chemical
Record UNII
229809935B
Record Status Validated
Record Version
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Details

Stereochemistry RACEMIC
Molecular Formula C21H27NO.ClH
Molecular Weight 345.906
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0
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Created by admin on Wed Aug 04 02:38:41 EDT 2021
Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of METHADONE HYDROCHLORIDE
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Systematic Names:

  • None recorded
Hide SMILES / InChI Show SMILES / InChI

SMILES

Cl.CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

FJQXCDYVZAHXNS-UHFFFAOYSA-N
InChI=1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
Name Type Language Details Access References
METHADONE HYDROCHLORIDE
EP   MART.   MI   ORANGE BOOK   USP   VANDF   WHO-DD  
Common Name
English  
WESTADONE
Brand Name
English  
PHENADONE HYDROCHLORIDE
Common Name
English  
NSC-19600
Code
English  
METHADOSE
Brand Name
English  
METHADONE HYDROCHLORIDE [WHO-DD]
Common Name
English  
METHADONE HYDROCHLORIDE [VANDF]
Common Name
English  
METHADONE HYDROCHLORIDE [USP-RS]
Common Name
English  
METHADONE HYDROCHLORIDE [USP MONOGRAPH]
Common Name
English  
METHADONE HYDROCHLORIDE [ORANGE BOOK]
Common Name
English  
METHADONE HYDROCHLORIDE [MI]
Common Name
English  
METHADONE HYDROCHLORIDE [JAN]
Common Name
English  
METHADONE HYDROCHLORIDE [EP]
Common Name
English  
METHADONE HYDROCHLORIDE [EP MONOGRAPH]
Common Name
English  
METHADONE HYDROCHLORIDE CII [USP-RS]
Common Name
English  
METHADONE HYDROCHLORIDE CII
USP-RS  
Common Name
English  
METHADONE HCL
Common Name
English  
MECODIN
Brand Name
English  
KETALGIN HYDROCHLORIDE
Brand Name
English  
HEPTADON
Brand Name
English  
FENADONE
Brand Name
English  
DOLOPHINE HYDROCHLORIDE
Brand Name
English  
DOLOPHINE
Brand Name
English  
DOLOFIN HYDROCHLORIDE
Brand Name
English  
DL-6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEPTANONE HYDROCHLORIDE
Common Name
English  
BUTALGIN
Brand Name
English  
AN-148
Code
English  
ADANON HYDROCHLORIDE
Brand Name
English  
6-(DIMETHYLAMINO)-4,4-DIPHENYL-3-HEPTANONE HYDROCHLORIDE
Systematic Name
English  
4,4-DIPHENYL-6-DIMETHYLAMINO-3-HEPTANONE HYDROCHLORIDE
Systematic Name
English  
3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, HYDROCHLORIDE (1:1)
Systematic Name
English  
3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, HYDROCHLORIDE
Systematic Name
English  
Classification Tree Code System Code Access References
DEA NO. 9250
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
NCI_THESAURUS C1506
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
NCI_THESAURUS C67413
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Code System Code Type Description Access References
CAS
70181-39-4
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
SUPERSEDED
CAS
70172-45-1
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
SUPERSEDED
CAS
1095-90-5
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
CAS
125-56-4
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
SUPERSEDED
EVMPD
SUB03203MIG
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
ChEMBL
CHEMBL651
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
DRUG BANK
DBSALT000346
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
ECHA (EC/EINECS)
214-140-7
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
EPA CompTox
1095-90-5
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
FDA UNII
229809935B
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
MERCK INDEX
M7286
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY Merck Index
NCI_THESAURUS
C638
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
PUBCHEM
14184
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
RS_ITEM_NUM
1398009
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY
RXCUI
218337
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
PRIMARY RxNorm
Related Record Type Details Access References
Structure of METHADONE
PARENT -> SALT/SOLVATE
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of DEXTROMETHADONE HYDROCHLORIDE
ENANTIOMER -> RACEMATE
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of LEVOMETHADONE HYDROCHLORIDE
ENANTIOMER -> RACEMATE
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of METHADONE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
Mediator Substance Details
none
ASSAY (TITRATION)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of METHADONE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
Mediator Substance Details
none
ASSAY (TITRATION)
USP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Related Record Type Details Access References
Structure of 2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE
METABOLITE INACTIVE -> PARENT
Mediator Substance Details
none
Cytochrome P450 enzymes, primarily CYP3A4, CYP2B6, and CYP2C19 and to a lesser extent CYP2C9 and CYP2D6, are responsible for conversion of methadone to EDDP and other inactive metabolites, which are excreted mainly in the urine.
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Related Record Type Details Access References
Structure of ISOMETHADONE
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (GC)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of ISOMETHADONE KETIMINE
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (GC)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of ISODIDIAVALO
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (GC)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of DIPHENYLACETONITRILE
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (GC)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Structure of DIDIAVALO
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (GC)
EP
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Related Record Type Details Access References
Structure of METHADONE
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:38:41 EDT 2021 , Edited by admin on Wed Aug 04 02:38:41 EDT 2021
Note Access References 
[Validation]WARNING:Each fragment should be present as a separate record in the database. Please register: CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
 
[Validation]WARNING:Each fragment should be present as a separate record in the database. Please register: Cl
Created Wed Aug 04 02:38:41 EDT 2021
Created By admin
Last Edited Wed Aug 04 02:38:41 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 METHADONE HYDROCHLORIDE CII [USP-RS] SRS_LOCATOR
2 FDA-SRS 2010 SRS NOMEN
3 SRS import [229809935B] SRS NOMEN Fri Apr 28 14:28:26 EDT 2017
4 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
5 USP DICTIONARY 2010 SRS NOMEN
6 METHADONE HYDROCHLORIDE [USP] SRS_LOCATOR
7 STN STN (SCIFINDER)
8 http://www.accessdata.fda.gov/spl/data/96006da6-d453-48c2-8648-7a76cd6954fb/96006da6-d453-48c2-8648-7a76cd6954fb.xml WEBSITE NOMEN
9 METHADONE HYDROCHLORIDE [VANDF] SRS_LOCATOR
10 USP 33 SRS NOMEN
11 NDF-RT SRS NOMEN
12 USP-RS SRS NOMEN
13 EP 10.5 EP
14 USP Dictionary 2010 SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
15 USP 36 METHADONE HYDROCHLORIDE MONOGRAPH USP NOMEN
16 WHO-DD SRS NOMEN
17 MERCK SRS NOMEN
18 STN STN (SCIFINDER)
19 ORANGE BOOK 2011 SRS NOMEN
20 METHADONE HYDROCHLORIDE [WHO-DD] SRS_LOCATOR
21 METHADONE HYDROCHLORIDE [EP] SRS_LOCATOR
22 GSRS System-generated Validation messages VALIDATION_MESSAGE Wed Aug 04 02:38:38 EDT 2021
23 EP 7.2 SRS NOMEN
24 MARTINDALE 2011 SRS NOMEN
25 EP 7.8 METHADONE HYDROCHLORIDE MONOGRAPH EUROPEAN PHARMACOPEIA NOMEN
26 JAN SRS PUBLIC_DOMAIN_RELEASE NOMEN
27 STN STN (SCIFINDER)
28 STN SRS NOMEN
29 STN STN (SCIFINDER)
30 http://www.rxlist.com/dolophine-drug.htm SRS NOMEN
31 METHADONE HYDROCHLORIDE [ORANGE BOOK] SRS_LOCATOR
32 SYSTEM
33 SRS CODE IMPORT SRS NOMEN Fri Apr 28 14:28:26 EDT 2017
34 USP 10/2020 USPNF
35 METHADONE HYDROCHLORIDE [MART.] SRS_LOCATOR
36 METHADONE HYDROCHLORIDE [MI] SRS_LOCATOR
37 ORANGE BOOK SRS NOMEN
38 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 02:38:37 EDT 2021
39 USP-RS USPNF
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H27NO
Molecular Weight 309.4452
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )