Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
1LGS5JRP31
Record Status Validated
Record Version
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Details

Stereochemistry RACEMIC
Molecular Formula C16H18N2
Molecular Weight 238.3275
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0
Created by admin on Wed Aug 04 06:03:55 EDT 2021
Edited by admin on Wed Aug 04 06:03:55 EDT 2021
Structure of NOMIFENSINE

Systematic Names:

  • None recorded

SMILES

CN1CC(C2=CC=CC=C2)C3=C(C1)C(N)=CC=C3

InChI

XXPANQJNYNUNES-UHFFFAOYSA-N
InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3
Name Type Language Details Access References
NOMIFENSINE
Domain Jurisdiction Naming Organization
drug  
INN  
HSDB   INN   MI   WHO-DD  
Official Name
English  
NOMIFENSINE [WHO-DD]
Common Name
English  
NOMIFENSINE [MI]
Common Name
English  
NOMIFENSINE [INN]
Common Name
English  
NOMIFENSINE [HSDB]
Common Name
English  
NOMIFENSIN
Brand Name
English  
LINAMIPHEN
Common Name
English  
ISOQUINOLINE, 8-AMINO-1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-
Systematic Name
English  
8-ISOQUINOLINAMINE, 1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-
Systematic Name
English  
2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-8-YLAMINE
Systematic Name
English  
1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-8-ISOQUINOLINAMINE
Systematic Name
English  
(+/-)-NOMIFENSINE
Common Name
English  
(+/-)-NOMIFENSIN
Common Name
English  
Classification Tree Code System Code Access References
WHO-ATC N06AX04
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
EPA PESTICIDE CODE 600075
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
NCI_THESAURUS C265
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
WHO-VATC QN06AX04
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
Code System Code Type Description Access References
CAS
24526-64-5
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
EVMPD
SUB09347MIG
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
ChEMBL
CHEMBL273575
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
DRUG BANK
DB04821
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
DRUG CENTRAL
1958
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
EPA CompTox
24526-64-5
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
FDA UNII
1LGS5JRP31
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
HSDB
7702
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
INN
2920
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
IUPHAR
4792
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
MERCK INDEX
M8030
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY Merck Index
MESH
D009627
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
NCI_THESAURUS
C72824
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
PUBCHEM
4528
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
RXCUI
7500
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY RxNorm
WIKIPEDIA
NOMIFENSINE
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
PRIMARY
Related Record Type Details Access References
METABOLIC ENZYME -> SUBSTRATE
Mediator Substance Details
none
MAJOR
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
SALT/SOLVATE -> PARENT
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLIC ENZYME -> SUBSTRATE
Mediator Substance Details
none
MAJOR
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
Related Record Type Details Access References
METABOLITE -> PARENT
Mediator Substance Details
IN VITRO
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
METABOLITE -> PARENT
Mediator Substance Details
none
IN VITRO
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLITE -> PARENT
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLITE -> PARENT
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
METABOLITE -> PARENT
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:58 EDT 2021 , Edited by admin on Wed Aug 04 06:03:58 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 06:03:55 EDT 2021 , Edited by admin on Wed Aug 04 06:03:55 EDT 2021
Created Wed Aug 04 06:03:55 EDT 2021
Created By admin
Last Edited Wed Aug 04 06:03:55 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 NOMIFENSINE [HSDB] SRS_LOCATOR
2 STN STN (SCIFINDER)
3 SYSTEM
4 NOMIFENSINE [MI] SRS_LOCATOR
5 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:04:09 EDT 2017
6 SRS import [1LGS5JRP31] SRS NOMEN Fri Apr 28 15:04:09 EDT 2017
7 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
8 HSDB SRS NOMEN
9 NOMIFENSINE [INN] SRS_LOCATOR
10 WHO-DD SRS NOMEN
11 USP Dictionary 2010; INN 2010 SRS NOMEN
12 Yu, Jian, et al. "Identification of multiple glutathione conjugates of 8-amino-2-methyl-4-phenyl-1, 2, 3, 4-tetrahydroisoquinoline maleate (nomifensine) in liver microsomes and hepatocyte preparations: evidence of the bioactivation of nomifensine." Drug metabolism and disposition 38.1 (2010): 46-60. JA PUBLIC_DOMAIN_RELEASE
13 USP Dictionary 2010 SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
14 Yu, Jian, et al. "Identification of multiple glutathione conjugates of 8-amino-2-methyl-4-phenyl-1, 2, 3, 4-tetrahydroisoquinoline maleate (nomifensine) in liver microsomes and hepatocyte preparations: evidence of the bioactivation of nomifensine." Drug metabolism and disposition 38.1 (2010): 46-60. JA PUBLIC_DOMAIN_RELEASE
15 MERCK INDEX SRS NOMEN
16 STN SRS NOMEN
17 Yu, Jian, Dean G. Brown, and Doug Burdette. "In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism." Drug metabolism and disposition 38.10 (2010): 1767-1778. JA PUBLIC_DOMAIN_RELEASE
18 Yu, Jian, Dean G. Brown, and Doug Burdette. "In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism." Drug metabolism and disposition 38.10 (2010): 1767-1778. JA PUBLIC_DOMAIN_RELEASE
19 Yu, Jian, Dean G. Brown, and Doug Burdette. "In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism." Drug metabolism and disposition 38.10 (2010): 1767-1778. JA PUBLIC_DOMAIN_RELEASE
20 NOMIFENSINE [WHO-DD] SRS_LOCATOR
21 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
22 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 06:03:53 EDT 2021
23 INN Proposed List 24 INN_LIST PUBLIC_DOMAIN_RELEASE
24 Yu, Jian, et al. "Identification of multiple glutathione conjugates of 8-amino-2-methyl-4-phenyl-1, 2, 3, 4-tetrahydroisoquinoline maleate (nomifensine) in liver microsomes and hepatocyte preparations: evidence of the bioactivation of nomifensine." Drug metabolism and disposition 38.1 (2010): 46-60. JA PUBLIC_DOMAIN_RELEASE

Molecular Formula C16H18N2
Molecular Weight 238.3275
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )