Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
1X96A704XV
Record Status Validated
Record Version
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Details

Stereochemistry ABSOLUTE
Molecular Formula C28H44N4O8
Molecular Weight 564.671
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0
Created by admin on Sat Jun 26 08:42:29 EDT 2021
Edited by GUEST on Wed Jul 21 16:18:25 EDT 2021
Structure of MIZAGLIFLOZIN

Systematic Names:

  • None recorded

SMILES

CC(C)C1=C(CC2=C(C)C=C(OCCCNCC(C)(C)C(N)=O)C=C2)C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=NN1

InChI

LREHMKLEOJAVMQ-TXKDOCKMSA-N
InChI=1S/C28H44N4O8/c1-15(2)21-19(25(32-31-21)40-26-24(36)23(35)22(34)20(13-33)39-26)12-17-7-8-18(11-16(17)3)38-10-6-9-30-14-28(4,5)27(29)37/h7-8,11,15,20,22-24,26,30,33-36H,6,9-10,12-14H2,1-5H3,(H2,29,37)(H,31,32)/t20-,22-,23+,24-,26+/m1/s1
Name Type Language Details Access References
MIZAGLIFLOZIN
Domain Jurisdiction Naming Organization
drug  
INN  
INN   WHO-DD  
Official Name
English  
PROPANAMIDE, 3-((3-(4-((3-(.BETA.-D-GLUCOPYRANOSYLOXY)-5-(1-METHYLETHYL)-1H-PYRAZOL-4-YL)METHYL)-3-METHYLPHENOXY)PROPYL)AMINO)-2,2-DIMETHYL-
Systematic Name
English  
MIZAGLIFLOZIN [WHO-DD]
Common Name
English  
MIZAGLIFLOZIN [INN]
Common Name
English  
KGA-3235 FREE BASE
Common Name
English  
GSK1614235 FREE BASE
Common Name
English  
GSK-1614235 FREE BASE
Common Name
English  
DSP-3235 FREE BASE
Common Name
English  
3-((3-(4-((3-(.BETA.-D-GLUCOPYRANOSYLOXY)-5-(PROPAN-2-YL)-1H-PYRAZOL-4-YL)METHYL)-3-METHYLPHENOXY)PROPYL)AMINO)-2,2-DIMETHYLPROPANAMIDE
Systematic Name
English  
Code System Code Type Description Access References
CAS
666843-10-3
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
PRIMARY
FDA UNII
1X96A704XV
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
PRIMARY
INN
10245
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
PRIMARY
NCI_THESAURUS
C166520
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
PRIMARY
PUBCHEM
10460535
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
PRIMARY
Related Record Type Details Access References
TARGET -> INHIBITOR
none
Mediator Substance Details
none
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
SALT/SOLVATE -> PARENT
none
Mediator Substance Details
none
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Sat Jun 26 08:42:29 EDT 2021 , Edited by admin on Sat Jun 26 08:42:29 EDT 2021
Created Sat Jun 26 08:42:29 EDT 2021
Created By admin
Last Edited Sat Jun 26 08:42:29 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 INN SRS NOMEN
2 INN Proposed List 114 INN_LIST PUBLIC_DOMAIN_RELEASE
3 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:27:26 EDT 2017
4 STN STN (SCIFINDER) NOMEN
5 STN STN (SCIFINDER)
6 MIZAGLIFLOZIN [INN] SRS_LOCATOR
7 STN SRS NOMEN
8 MIZAGLIFLOZIN [WHO-DD] SRS_LOCATOR
9 dump-public-2021-06-23_UPDATED.gsrs BATCH_IMPORT Sat Jun 26 08:42:28 EDT 2021
10 INN LIST 114 SRS NOMEN
11 Ohno, Hitoshi, et al. "Absorption, disposition, metabolism and excretion of [14C] mizagliflozin, a novel selective SGLT1 inhibitor, in rats." Xenobiotica 49.4 (2019): 463-473. JA NOMEN PUBLIC_DOMAIN_RELEASE
12 NCIT NCI THESAURUS
13 Inoue, Toshihiro, et al. "Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation." European journal of pharmacology 806 (2017): 25-31. JA NOMEN PUBLIC_DOMAIN_RELEASE POT
14 WHO-DD SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
15 SYSTEM
16 SRS import [1X96A704XV] SRS NOMEN Fri Apr 28 15:27:26 EDT 2017
17 WHO DRUG DICTIONARY WHO DRUG DICTIONARY NOMEN

Molecular Formula C28H44N4O8
Molecular Weight 564.671
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED