Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
L35JN3I7SJ
Record Status Validated
Record Version
Show Definitional References Hide Definitional References
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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H32N2O5
Molecular Weight 416.5106
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0
Created by admin on Sun Feb 07 19:44:26 EST 2021
Edited by admin on Sun Feb 07 19:44:26 EST 2021
Structure of RAMIPRIL

Systematic Names:

  • None recorded

SMILES

[H][C@@]12CCC[C@]1([H])N([C@@H](C2)C(O)=O)C(=O)[C@H](C)N[C@@H](CCC3=CC=CC=C3)C(=O)OCC

InChI

HDACQVRGBOVJII-JBDAPHQKSA-N
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
Name Type Language Details Access References
RAMIPRIL
Domain Jurisdiction Naming Organization
drug  
USAN   INN  
EP   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
Official Name
English  
VESDIL
Brand Name
English  
UNIPRIL
Brand Name
English  
TRITACE
Brand Name
English  
TRIATEC
Common Name
English  
RAMIPRIL, (+)-
Common Name
English  
RAMIPRIL [WHO-DD]
Common Name
English  
RAMIPRIL [VANDF]
Common Name
English  
RAMIPRIL [USP]
Common Name
English  
RAMIPRIL [USP-RS]
Common Name
English  
RAMIPRIL [USP MONOGRAPH]
Common Name
English  
RAMIPRIL [USAN]
Common Name
English  
RAMIPRIL [ORANGE BOOK]
Common Name
English  
RAMIPRIL [MI]
Common Name
English  
RAMIPRIL [MART.]
Common Name
English  
RAMIPRIL [JAN]
Common Name
English  
RAMIPRIL [INN]
Common Name
English  
RAMIPRIL [EP]
Common Name
English  
RAMIPRES
Brand Name
English  
RAMACE
Brand Name
English  
PRAMACE
Brand Name
English  
POLYCAP COMPONENT RAMIPRIL
Brand Name
English  
HOPACE
Brand Name
English  
HOE-498
Code
English  
HOE 498
Code
English  
ECATOR
Brand Name
English  
DELIX
Brand Name
English  
CYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID, 1-(2-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S-(1(R*(R*)),2.ALPHA.,3A.BETA.,6A.BETA.))-
Common Name
English  
CYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID, 1-((2S)-2-(((1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S,3AS,6AS)-
Common Name
English  
CORPRIL
Brand Name
English  
CARDACE
Brand Name
English  
C09AA05
Code
English  
ALTACE
Brand Name
English  
(2S,3AS,6AS)-1-((S)-N-((S)-1-CARBOXY-3-PHENYLPROPYL)ALANYL)OCTAHYDROCYCLOPENTA(B)PYRROLE-2-CARBOXYLIC ACID, 1-ETHYL ESTER
Common Name
English  
Classification Tree Code System Code Access References
WHO-ATC C09BB07
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C09BB05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C10BX04
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C09BA05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C09BX03
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C09AA05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-ATC C10BX06
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
LIVERTOX 832
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
NCI_THESAURUS C247
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
NDF-RT N0000000181
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
NDF-RT N0000175562
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-VATC QC09AA05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-VATC QC09BA05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-VATC QC09BB05
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-VATC QC09BB07
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
WHO-VATC QC10BX04
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
Code System Code Type Description Access References
CAS
87333-19-5
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
EVMPD
SUB10248MIG
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
ChEMBL
CHEMBL1168
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
DRUG BANK
DB00178
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
DRUG CENTRAL
2356
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
EPA CompTox
87333-19-5
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
FDA UNII
L35JN3I7SJ
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
INN
5561
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
IUPHAR
6339
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
LACTMED
Ramipril
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
MERCK INDEX
M9491
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY Merck Index
MESH
D017257
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
NCI_THESAURUS
C29411
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
PUBCHEM
5362129
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
RXCUI
35296
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY RxNorm
WIKIPEDIA
RAMIPRIL
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
PRIMARY
Related Record Type Details Access References
BASIS OF STRENGTH->SUBSTANCE
Mediator Substance Details
none
ASSAY (HPLC)
USP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
METABOLIC ENZYME -> SUBSTRATE
Mediator Substance Details
none
Vmax
Created by admin on Sun Feb 07 19:44:26 EST 2021 , Edited by admin on Sun Feb 07 19:44:26 EST 2021
BASIS OF STRENGTH->SUBSTANCE
Mediator Substance Details
none
ASSAY (TITRATION)
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
Related Record Type Details Access References
METABOLITE ACTIVE -> PRODRUG
Mediator Substance Details
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
Related Record Type Details Access References
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
For the calculation of contents, multiply the peak areas by 2.4
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
UNSPECIFIED
EP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Sun Feb 07 19:44:27 EST 2021 , Edited by admin on Sun Feb 07 19:44:27 EST 2021
Name Property Type Amount Referenced Substance Defining Parameters Access References
Biological Half-life PHARMACOKINETIC Elimination
PHARMACOKINETIC
Elimination
PHARMACOKINETIC
Note Access References
[Validation]WARNING:Code 'N0000000181'[NDF-RT] collides (possible duplicate) with existing code & codeSystem for substance:
[UDM7Q7QWP8]BENAZEPRIL
[Validation]WARNING:Code 'C10BX06'[WHO-ATC] collides (possible duplicate) with existing code & codeSystem for substance:
[R16CO5Y76E]ASPIRIN
[Validation]WARNING:Code 'C10BX04'[WHO-ATC] collides (possible duplicate) with existing code & codeSystem for substance:
[AGG2FN16EV]SIMVASTATIN
[Validation]WARNING:Code 'N0000175562'[NDF-RT] collides (possible duplicate) with existing code & codeSystem for substance:
[UDM7Q7QWP8]BENAZEPRIL
[Validation]WARNING:Code 'QC10BX04'[WHO-VATC] collides (possible duplicate) with existing code & codeSystem for substance:
[AGG2FN16EV]SIMVASTATIN
Created Sun Feb 07 19:44:26 EST 2021
Created By admin
Last Edited Sun Feb 07 19:44:26 EST 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 INN 2010 SRS NOMEN
2 SRS import [L35JN3I7SJ] SRS NOMEN Fri Apr 28 14:27:52 EDT 2017
3 USP 36 RAMIPRIL MONOGRAPH USP NOMEN
4 Patel, Anil, et al. "Preservation of Bioavailability of Ingredients and Lack of Drug-Drug Interactions in a Novel Five-Ingredient Polypill (Polycap™)." American journal of cardiovascular drugs 10.2 (2010): 95-103. JA
5 INN Proposed List 52 INN_LIST PUBLIC_DOMAIN_RELEASE
6 RAMIPRIL [INN] SRS_LOCATOR
7 USP DICTIONARY 2011 SRS NOMEN
8 RAMIPRIL [MART.] SRS_LOCATOR
9 RAMIPRIL [USP-RS] SRS_LOCATOR
10 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
11 USP DICTIONARY 2010 SRS NOMEN
12 RAMIPRIL [ORANGE BOOK] SRS_LOCATOR
13 SRS CODE IMPORT SRS NOMEN Fri Apr 28 14:27:52 EDT 2017
14 Thomsen, Ragnar, Henrik B. Rasmussen, and Kristian Linnet. "In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors." DRUG METABOLISM AND DISPOSITION 42 (2014): 126-133. JA
15 RAMIPRIL [MI] SRS_LOCATOR
16 FDA_SRS SRS NOMEN
17 GSRS System-generated Validation messages VALIDATION_MESSAGE Sun Feb 07 19:44:19 EST 2021
18 EP 7.8 RAMIPRIL MONOGRAPH EUROPEAN PHARMACOPEIA NOMEN
19 RAMIPRIL [VANDF] SRS_LOCATOR
20 USP/NF SRS NOMEN
21 MERCK INDEX SRS NOMEN
22 http://www.drugs.com/international/triatec.html SRS NOMEN
23 GSRS System-generated Validation messages VALIDATION_MESSAGE Sun Feb 07 19:44:19 EST 2021
24 WHO-DD SRS NOMEN
25 USP Dictionary 2010 SRS NOMEN
26 USP 33 SRS NOMEN
27 RAMIPRIL [USP] SRS_LOCATOR
28 STN STN (SCIFINDER)
29 USP 10/2020 USPNF
30 RAMIPRIL [USAN] SRS_LOCATOR
31 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
32 JAN SRS NOMEN PUBLIC_DOMAIN_RELEASE
33 Drug Information Handbook, 2016-2017 - 25th edition; Lexicomp Drug Reference Handbook; ISBN13: 9781591953531 BOOK PUBLIC_DOMAIN_RELEASE
34 ORANGE BOOK 2011 SRS NOMEN
35 USP DICTIONARY SRS NOMEN
36 MARTINDALE 2011 SRS NOMEN
37 ATC CODE 2009 SRS NOMEN
38 USP Dictionary SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
39 EP 7.2 SRS NOMEN
40 RAMIPRIL [WHO-DD] SRS_LOCATOR
41 RAMIPRIL [EP] SRS_LOCATOR
42 STN SRS NOMEN
43 European Pharmacopoeia Online 9.8, Ramipril Monograph EP PUBLIC_DOMAIN_RELEASE
44 WHO 2009 INN NOMEN
45 https://en.wikipedia.org/wiki/Ramipril WIKI
46 NDF-RT SRS NOMEN
47 SYSTEM

Molecular Formula C23H32N2O5
Molecular Weight 416.5106
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED