Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Protein
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
F202H3PMO2
Record Status Validated
Record Version
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Name Type Language Details Access References
SODIUM-DEPENDENT DOPAMINE TRANSPORTER
Common Name
English  
SOLUTE CARRIER FAMILY 6 MEMBER 3
Common Name
English  
SLC6A3
Common Name
English  
DAT1
Common Name
English  
DAT
Common Name
English  
DA TRANSPORTER
Common Name
English  
Code System Code Type Description Access References
CAS
816154-03-7
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
PRIMARY
FDA UNII
F202H3PMO2
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
PRIMARY
UNIPROT
Q01959
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
PRIMARY
WIKIPEDIA
Dopamine transporter
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
PRIMARY
From To
1_180 1_189
1_306 2_306
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_181
N 1_188
N 1_205
N 2_181
N 2_188
N 2_205
Related Record Type Details Access References
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TRANSPORTER
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TRANSPORTER
Mediator Substance Details
none
IN-VITRO
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TRANSPORTER
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
Mediator Substance Details
none
IC50
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
Mediator Substance Details
none
Ki
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
RADIOLIGAND->TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
RADIOLIGAND->TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR->OFF-TARGET
Mediator Substance Details
none
BINDING
IC50
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
RADIOLIGAND->TARGET
Mediator Substance Details
none
Ki
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
RADIOLIGAND->TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
Mediator Substance Details
none
IN-VITRO
IC50
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
Mediator Substance Details
none
BINDING
IC50
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
INHIBITOR -> TARGET
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
LIGAND->TRANSPORTER
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 22:04:16 EDT 2021 , Edited by admin on Wed Aug 04 22:04:16 EDT 2021
Name Property Type Amount Referenced Substance Defining Parameters Access References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
0
Created Wed Aug 04 22:04:13 EDT 2021
Created By admin
Last Edited Wed Aug 04 22:04:13 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
2 Literature other PUBLIC_DOMAIN_RELEASE
3 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
4 STN STN (SCIFINDER)
5 https://en.wikipedia.org/wiki/Dopamine_receptor_D2 JA
6 LITERATURE JA PUBLIC_DOMAIN_RELEASE
7 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
8 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 22:04:13 EDT 2021
9 https://www.accessdata.fda.gov/drugsatfda_docs/nda/2017/208447Orig1s000MultidisciplineR.pdf NDA PUBLIC REVIEW PUBLIC_DOMAIN_RELEASE
10 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
11 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
12 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
13 STN (SCIFINDER) STN (SCIFINDER) NOMEN
14 literature JA PUBLIC_DOMAIN_RELEASE
15 LITERATURE JA PUBLIC_DOMAIN_RELEASE
16 Proc Nat Acad Sci, 98, 10055-60 (2001) JA
17 J Biol Chem, 278, 45045-45048 (2003) JA
18 208447Orig1s000 MULTI-DISCIPLINE REVIEW NDA PUBLIC REVIEW NOMEN CLIN
19 Q01959 UNIPROT NOMEN PUBLIC_DOMAIN_RELEASE
20 https://www.accessdata.fda.gov/drugsatfda_docs/nda/2011/022454sOrig1s000ClinPharmR.pdf NDA PUBLIC REVIEW PUBLIC_DOMAIN_RELEASE
21 Dopamine transporter WIKI NOMEN
22 Yoder, Karmen K., et al. "Dopamine transporter binding in rat striatum: a comparison of [O-methyl-11C] ?-CFT and [N-methyl-11C] ?-CFT." Nuclear medicine and biology 36.1 (2009): 11-16. JA NOMEN PUBLIC_DOMAIN_RELEASE POT
23 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
24 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
25 Eshleman, Amy J., et al. "Substituted methcathinones differ in transporter and receptor interactions." Biochemical pharmacology 85.12 (2013): 1803-1815. JA
26 Schou, Magnus, et al. "Synthesis, radiolabeling and preliminary in vivo evaluation of [18F] FE-PE2I, a new probe for the dopamine transporter." Bioorganic & medicinal chemistry letters 19.16 (2009): 4843-4845. JA
27 Front. Pharmacol., 31 March 2016, Declercq, LD, et.al. JA PUBLIC_DOMAIN_RELEASE
28 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
29 LITERATURE JA PUBLIC_DOMAIN_RELEASE
30 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
31 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
32 https://www.phrma.org/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/PDF/MID_Mental-Illness-2019-Drug-List_FINAL.pdf WEB PAGE
33 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
34 https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/211230Orig1Orig2s000PharmR.pdf NDA PUBLIC REVIEW PUBLIC_DOMAIN_RELEASE
35 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
36 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE
37 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
38 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
39 Yoder, Karmen K., et al. "Dopamine transporter binding in rat striatum: a comparison of [O-methyl-11C] ?-CFT and [N-methyl-11C] ?-CFT." Nuclear medicine and biology 36.1 (2009): 11-16. JA NOMEN PUBLIC_DOMAIN_RELEASE POT SYNTH
40 Schou, Magnus, et al. "Synthesis, radiolabeling and preliminary in vivo evaluation of [18F] FE-PE2I, a new probe for the dopamine transporter." Bioorganic & medicinal chemistry letters 19.16 (2009): 4843-4845. JA
41 Schou, Magnus, et al. "Synthesis, radiolabeling and preliminary in vivo evaluation of [18F] FE-PE2I, a new probe for the dopamine transporter." Bioorganic & medicinal chemistry letters 19.16 (2009): 4843-4845. JA PUBLIC_DOMAIN_RELEASE
42 WIKI WIKI PUBLIC_DOMAIN_RELEASE
43 WIKI WIKI PUBLIC_DOMAIN_RELEASE
44 WIK WIKI NOMEN PUBLIC_DOMAIN_RELEASE
45 https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/211230Orig1Orig2s000PharmR.pdf NDA PUBLIC REVIEW PUBLIC_DOMAIN_RELEASE
46 Generated from relationship on:'ARMODAFINIL' SYSTEM
47 McCann, Una D., et al. "Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C] WIN-35,428." Journal of Neuroscience 18.20 (1998): 8417-8422. JA CLIN NOMEN PUBLIC_DOMAIN_RELEASE POT
48 WIKI WIKI NOMEN PUBLIC_DOMAIN_RELEASE