Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
BO9LE4QFZF
Record Status Validated
Record Version
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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H12N2O4
Molecular Weight 224.2133
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0
Created by admin on Wed Aug 04 02:22:30 EDT 2021
Edited by admin on Wed Aug 04 02:22:30 EDT 2021
Structure of STAVUDINE

Systematic Names:

  • None recorded

SMILES

CC1=CN([C@@H]2O[C@H](CO)C=C2)C(=O)NC1=O

InChI

XNKLLVCARDGLGL-JGVFFNPUSA-N
InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1
Name Type Language Details Access References
STAVUDINE
Domain Jurisdiction Naming Organization
drug  
USAN   INN  
EMA EPAR   EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   WHO-DD   WHO-IP  
Official Name
English  
ZIDOVUDINE IMPURITY A [WHO-IP]
Common Name
English  
ZIDOVUDINE IMPURITY A [EP]
Common Name
English  
ZERIT
Brand Name
English  
THYMIDINE, 2',3'-DIDEHYDRO-3'-DEOXY-
Systematic Name
English  
STAVUDINUM [WHO-IP LATIN]
Common Name
English  
STAVUDINE [WHO-IP]
Common Name
English  
STAVUDINE [WHO-DD]
Common Name
English  
STAVUDINE [USP-RS]
Common Name
English  
STAVUDINE [USP MONOGRAPH]
Common Name
English  
STAVUDINE [USAN]
Common Name
English  
STAVUDINE [ORANGE BOOK]
Common Name
English  
STAVUDINE [MI]
Common Name
English  
STAVUDINE [MART.]
Common Name
English  
STAVUDINE [INN]
Common Name
English  
STAVUDINE [HSDB]
Common Name
English  
STAVUDINE [EP]
Common Name
English  
STAVUDINE [EP MONOGRAPH]
Common Name
English  
STAVUDINE [EMA EPAR]
Common Name
English  
STAVUDINE (DT4) [VANDF]
Common Name
English  
STAVUDINE (D4T) [VANDF]
Common Name
English  
SANILVUDINE [JAN]
Common Name
English  
SANILVUDINE
JAN  
Common Name
English  
NSC-759897
Code
English  
NSC-163661
Code
English  
D4T
Code
English  
D-4T
Code
English  
1-(2,3-DIDEOXY-.BETA.-D-GLYCERO-PENT-2-ENOFURANOSYL)THYMINE
Common Name
English  
1-((2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
Common Name
English  
Classification Tree Code System Code Access References
WHO-ATC J05AR07
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
WHO-ATC J05AF04
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
EMA ASSESSMENT REPORTS ZERIT (AUTHORIZED: HIV INFECTIONS)
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
LIVERTOX 899
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NCI_THESAURUS C97452
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NDF-RT N0000009947
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NDF-RT N0000175459
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NDF-RT N0000175459
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NDF-RT N0000175459
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
NDF-RT N0000175462
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
WHO-ESSENTIAL MEDICINES LIST 6.4.2.1
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
WHO-ESSENTIAL MEDICINES LIST 6.4.2.3 (LAM/NEV/STA)
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
WHO-VATC QJ05AF04
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
WHO-VATC QJ05AR07
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
Code System Code Type Description Access References
CAS
3056-17-5
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
EVMPD
SUB10642MIG
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
ChEMBL
CHEMBL991
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
DRUG BANK
DB00649
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
DRUG CENTRAL
2478
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
EPA CompTox
3056-17-5
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
FDA UNII
BO9LE4QFZF
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
HSDB
7338
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
INN
6775
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
LACTMED
Stavudine
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
MERCK INDEX
M10199
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY Merck Index
MESH
D018119
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
NCI_THESAURUS
C1428
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
PUBCHEM
18283
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
RS_ITEM_NUM
1620209
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
RXCUI
59763
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY RxNorm
WHO INTERNATIONAL PHARMACOPEIA
STAVUDINE
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY Description: A white to almost white powder. Solubility: Soluble in water and sparingly soluble in ethanol (~750 g/l) TS. Category: Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor). Storage: Stavudine should be kept in a well-closed container, protected from light. Additional information: Stavudine may exhibit polymorphism. Definition: Stavudine contains not less than 97.0% and not more than 103.0% of C10H12N2O4, calculated with reference to the dried substance.
WIKIPEDIA
STAVUDINE
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
PRIMARY
Related Record Type Details Access References
EXCRETED UNCHANGED
Mediator Substance Details
none
AMOUNT EXCRETED
URINE
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
Related Record Type Details Access References
METABOLITE -> PARENT
Mediator Substance Details
none
MINOR
URINE
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
METABOLITE -> PARENT
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
METABOLITE ACTIVE -> PARENT
Mediator Substance Details
none
MAJOR
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
METABOLITE -> PARENT
Mediator Substance Details
none
MINOR
URINE
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
Related Record Type Details Access References
IMPURITY -> PARENT
Mediator Substance Details
none
Water (2.5.12): maximum 0.5 per cent, determined on 0.500 g.
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
Amount Not Specified
INTERNATIONAL PHARMACOPEIA
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
PARENT -> IMPURITY
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Wed Aug 04 02:22:31 EDT 2021 , Edited by admin on Wed Aug 04 02:22:31 EDT 2021
PARENT -> IMPURITY
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 02:22:30 EDT 2021 , Edited by admin on Wed Aug 04 02:22:30 EDT 2021
Name Property Type Amount Referenced Substance Defining Parameters Access References
Tmax PHARMACOKINETIC ORAL ADMINISTRATION

Biological Half-life PHARMACOKINETIC ORAL ADMINISTRATION

Note Access References
[Validation]WARNING:Code 'J05AR07'[WHO-ATC] collides (possible duplicate) with existing code & codeSystem for substance:
[2T8Q726O95]LAMIVUDINE
[Validation]WARNING:Code 'N0000175462'[NDF-RT] collides (possible duplicate) with existing code & codeSystem for substance:
[2T8Q726O95]LAMIVUDINE
[Validation]WARNING:Code 'QJ05AR07'[WHO-VATC] collides (possible duplicate) with existing code & codeSystem for substance:
[99DK7FVK1H]NEVIRAPINE
[Validation]WARNING:Code 'N0000009947'[NDF-RT] collides (possible duplicate) with existing code & codeSystem for substance:
[G70B4ETF4S]EMTRICITABINE
[Validation]WARNING:Code 'N0000175459'[NDF-RT] collides (possible duplicate) with existing code & codeSystem for substance:
[G70B4ETF4S]EMTRICITABINE
[Validation]WARNING:Code '6.4.2.1'[WHO-ESSENTIAL MEDICINES LIST] collides (possible duplicate) with existing code & codeSystem for substance:
[2T8Q726O95]LAMIVUDINE
[Validation]WARNING:Code '6.4.2.3 (LAM/NEV/STA)'[WHO-ESSENTIAL MEDICINES LIST] collides (possible duplicate) with existing code & codeSystem for substance:
[2T8Q726O95]LAMIVUDINE
Created Wed Aug 04 02:22:30 EDT 2021
Created By admin
Last Edited Wed Aug 04 02:22:30 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 INN Proposed List 65 INN_LIST PUBLIC_DOMAIN_RELEASE
2 EP 10.5 EP
3 EP 7.2 SRS NOMEN
4 JAN SRS NOMEN
5 STAVUDINE [WHO-DD] SRS_LOCATOR
6 WHO-IP SRS NOMEN
7 SYSTEM
8 EMA SRS NOMEN
9 Zhou, Lian, et al. "Disposition of [1?-14C] stavudine after oral administration to humans." Drug metabolism and disposition 38.4 (2010): 655-666. JA PUBLIC_DOMAIN_RELEASE
10 THE INTERNATIONAL PHARMACOPOEIA FIFTH EDITION WEBSITE NOMEN
11 STAVUDINE (D4T) [VANDF] SRS_LOCATOR
12 STAVUDINE [USP] SRS_LOCATOR
13 SCIFINDER SRS NOMEN
14 STAVUDINE [INN] SRS_LOCATOR
15 WHO-DD SRS NOMEN
16 STAVUDINE [EMA EPAR] SRS_LOCATOR
17 European Pharmacopoeia Online 9.8, Stavudine Monograph EP PUBLIC_DOMAIN_RELEASE
18 STAVUDINE [USAN] SRS_LOCATOR
19 EP 9.7 Zidovudine Monograph EP NOMEN PUBLIC_DOMAIN_RELEASE
20 STAVUDINE [HSDB] SRS_LOCATOR
21 STAVUDINE [ORANGE BOOK] SRS_LOCATOR
22 SRS CODE IMPORT SRS NOMEN Fri Apr 28 14:38:29 EDT 2017
23 THE INTERNATIONAL PHARMACOPOEIA FIFTH EDITION WEBSITE NOMEN
24 USP DICTIONARY 2010 SRS NOMEN
25 http://www.accessdata.fda.gov/spl/data/7e130f8d-4de7-434d-b00f-33b45f1e7d71/7e130f8d-4de7-434d-b00f-33b45f1e7d71.xml WEBSITE NOMEN
26 STAVUDINE [EP] SRS_LOCATOR
27 USP 33 SRS NOMEN
28 USP DICTIONARY 2011 SRS NOMEN
29 EP EP PUBLIC_DOMAIN_RELEASE NOMEN
30 ORANGE BOOK 2011 SRS NOMEN
31 DMD APRIL 2010 VOL. 38 NO. 4 655-666 JOURNAL ARTICLE NOMEN
32 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 02:22:25 EDT 2021
33 European Pharmacopoeia Online 9.8, Stavudine Monograph EP PUBLIC_DOMAIN_RELEASE
34 STAVUDINE [WHO-IP] SRS_LOCATOR
35 MARTINDALE 2011 SRS NOMEN
36 NCI NCI DRUG DICTIONARY
37 GSRS System-generated Validation messages VALIDATION_MESSAGE Wed Aug 04 02:22:30 EDT 2021
38 STAVUDINE [MI] SRS_LOCATOR
39 DMD, APRIL 2010 VOL. 38 NO. 4 655-666 JOURNAL ARTICLE NOMEN
40 European Pharmacopoeia Online 9.8, Stavudine Monograph EP PUBLIC_DOMAIN_RELEASE
41 STN STN (SCIFINDER)
42 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
43 USP 10/2020 USPNF
44 USP Dictionary 2010 SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
45 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
46 THE INTERNATIONAL PHARMACOPOEIA FIFTH EDITION WEBSITE NOMEN
47 NDF-RT SRS NOMEN
48 SANILVUDINE [JAN] SRS_LOCATOR
49 EP 7.8 SRS NOMEN
50 HTTP://WWW.ACCESSDATA.FDA.GOV/SPL/DATA/7E130F8D-4DE7-434D-B00F-33B45F1E7D71/7E130F8D-4DE7-434D-B00F-33B45F1E7D71.XML WEBSITE NOMEN
51 USP/NF SRS NOMEN
52 IP WHO INTERNATIONAL PHARMACOPOEIA NOMEN PUBLIC_DOMAIN_RELEASE
53 HSDB SRS NOMEN
54 STAVUDINE [MART.] SRS_LOCATOR
55 USP42-NF37 - 4079, Stavudine Monograph USPNF PUBLIC_DOMAIN_RELEASE
56 European Pharmacopoeia Online 9.8, Stavudine Monograph EP PUBLIC_DOMAIN_RELEASE
57 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
58 USP DICTIONARY SRS NOMEN
59 STAVUDINE [USP-RS] SRS_LOCATOR
60 ANTIMICROB. AGENTS CHEMOTHER. MAY 2004 VOL. 48 NO. 5 1640-1646 JOURNAL ARTICLE NOMEN
61 SRS import [BO9LE4QFZF] SRS NOMEN Fri Apr 28 14:38:29 EDT 2017
62 MERCK INDEX SRS NOMEN

Molecular Formula C10H12N2O4
Molecular Weight 224.2133
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED