Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
F5I3T42BXC
Record Status Validated
Record Version
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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H14N2.Pt.H2O7P2
Molecular Weight 485.232
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0
Created by admin on Wed Aug 04 01:58:07 EDT 2021
Edited by admin on Wed Aug 04 01:58:07 EDT 2021
Structure of IMIFOPLATIN

Systematic Names:

  • None recorded

SMILES

[Pt++].N[C@@H]1CCCC[C@H]1N.OP([O-])(=O)OP(O)([O-])=O

InChI

SCMHTXQHAHWVSX-BNTLRKBRSA-L
InChI=1S/C6H14N2.H4O7P2.Pt/c7-5-3-1-2-4-6(5)8;1-8(2,3)7-9(4,5)6;/h5-6H,1-4,7-8H2;(H2,1,2,3)(H2,4,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1
Name Type Language Details Access References
IMIFOPLATIN
Domain Jurisdiction Naming Organization
USAN   INN  
Official Name
English  
PT-112
Code
English  
PT 112 [WHO-DD]
Common Name
English  
PLATINATE(2-), ((1R,2R)-1,2-CYCLOHEXANEDIAMINE-.KAPPA.N1,.KAPPA.N2)(DIPHOSPHATO(4-)-.KAPPA.O,.KAPPA.O'')-, HYDROGEN (1:2), (SP-4-2)-
Systematic Name
English  
IMIFOPLATIN [USAN]
Common Name
English  
IMIFOPLATIN [INN]
Common Name
English  
DIHYDROGEN (SP-4-2)-((1R,2R)-CYCLOHEXANE-1,2-DIAMINE-.KAPPA.2N1,N2)(DIPHOSPHATO(4)-.KAPPA.2O1,O3)PLATINATE(2)
Systematic Name
English  
CYCLOHEXANEDIAMINE PYROPHOSPHATOPLATINUM(II), (1R,2R)-
Systematic Name
English  
CYCLOHEXANE-(1R,2R)-DIAMINEPLATINUM(II) DIPHOSPHATE
Systematic Name
English  
1,2-CYCLOHEXANEDIAMINE PYROPHOSPHATOPLATINUM(II), (R,R)-
Common Name
English  
Classification Tree Code System Code Access References
FDA ORPHAN DRUG 613617
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
FDA ORPHAN DRUG 654818
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
Code System Code Type Description Access References
CAS
1339960-28-9
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
EPA CompTox
1339960-28-9
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
FDA UNII
F5I3T42BXC
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
INN
10949
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
NCI_THESAURUS
C121375
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
PUBCHEM
25241709
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
PRIMARY
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Wed Aug 04 01:58:07 EDT 2021 , Edited by admin on Wed Aug 04 01:58:07 EDT 2021
Note Access References
[Validation]WARNING:Each fragment should be present as a separate record in the database. Please register: [Pt++]
[Validation]WARNING:Each fragment should be present as a separate record in the database. Please register: N[C@@H]1CCCC[C@H]1N
[Validation]WARNING:Each fragment should be present as a separate record in the database. Please register: OP(O)(=O)OP([O-])([O-])=O
Created Wed Aug 04 01:58:07 EDT 2021
Created By admin
Last Edited Wed Aug 04 01:58:07 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 fda orphan drug ORPHAN DRUG PUBLIC_DOMAIN_RELEASE
2 INN Proposed List 121 INN_LIST PUBLIC_DOMAIN_RELEASE
3 STN SRS NOMEN
4 USAN COUN 2021 USANCOUN PUBLIC_DOMAIN_RELEASE
5 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Wed Aug 04 01:58:06 EDT 2021
6 STN STN (SCIFINDER)
7 Karp, Daniel D., et al. "A phase I study of PT-112 in advanced solid tumors." (2017): 2519-2519. MEETING ABSTRACT
8 FDA_SRS SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
9 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
10 SYSTEM
11 who WHO DRUG DICTIONARY PUBLIC_DOMAIN_RELEASE NOMEN
12 SRS import [F5I3T42BXC] SRS NOMEN Fri Apr 28 15:05:39 EDT 2017
13 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:05:39 EDT 2017
14 GSRS System-generated Validation messages VALIDATION_MESSAGE Wed Aug 04 01:58:07 EDT 2021

Molecular Formula Pt2+
Molecular Weight 195.084
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H14N2
Molecular Weight 114.1888
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula H2O7P22-
Molecular Weight 175.9592
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE