Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.7.1
Substance Class Chemical
Record UNII
87T4T8BO2E
Record Status Validated
Record Version
This is an older version of the record
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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H25NOS
Molecular Weight 315.473
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0
Created by admin on Tue Aug 03 21:58:44 EDT 2021
Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Structure of ROTIGOTINE

Systematic Names:

  • None recorded

SMILES

CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C2)C=CC=C3O

InChI

KFQYTPMOWPVWEJ-INIZCTEOSA-N
InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1
Name Type Language Details Access References
ROTIGOTINE
Domain Jurisdiction Naming Organization
drug  
USAN   INN  
EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
Official Name
English  
SPM-962
Code
English  
SPM 962
Code
English  
ROTIGOTINE [WHO-DD]
Common Name
English  
ROTIGOTINE [VANDF]
Common Name
English  
ROTIGOTINE [USP-RS]
Common Name
English  
ROTIGOTINE [USP MONOGRAPH]
Common Name
English  
ROTIGOTINE [USAN]
Common Name
English  
ROTIGOTINE [ORANGE BOOK]
Common Name
English  
ROTIGOTINE [MI]
Common Name
English  
ROTIGOTINE [MART.]
Common Name
English  
ROTIGOTINE [JAN]
Common Name
English  
ROTIGOTINE [INN]
Common Name
English  
ROTIGOTINE [EP MONOGRAPH]
Common Name
English  
ROTIGOTINE [EMA EPAR]
Common Name
English  
NEUPRO
Brand Name
English  
LEGANTO
Brand Name
English  
1-NAPHTHALENOL, 5,6,7,8-TETRAHYDRO-6-(PROPYL(2-(2-THIENYL)ETHYL)AMINO-(6S)-
Common Name
English  
(6S)-6-(PROPYL(2-(2-THIENYL)ETHYL)AMINO)-5,6,7,8-TETRAHYDRO-1-NAPHTHALENOL
Systematic Name
English  
(-)-(S)-5,6,7,8-TETRAHYDRO-6-(PROPYL(2-(2-THIENYL)ETHYL)AMINO)-1-NAPHTHOL
Systematic Name
English  
Classification Tree Code System Code Access References
WHO-ATC N04BC09
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
EMA ASSESSMENT REPORTS LEGANTO (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
EMA ASSESSMENT REPORTS LEGANTO (AUTHORIZED: RESTLESS LEGS SYNDROME)
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
EMA ASSESSMENT REPORTS NEUPRO (AUTHORIZED: PARKINSON DISEASE)
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
EMA ASSESSMENT REPORTS NEUPRO (AUTHORIZED: RESTLESS LEGS SYNDROME)
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
NCI_THESAURUS C66884
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
WHO-VATC QN04BC09
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Code System Code Type Description Access References
CAS
99755-59-6
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
EVMPD
SUB21254
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
ChEMBL
CHEMBL1303
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
DRUG BANK
DB05271
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
DRUG CENTRAL
2407
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
EPA CompTox
99755-59-6
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
FDA UNII
87T4T8BO2E
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
HSDB
8254
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
INN
7897
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
IUPHAR
941
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
LACTMED
Rotigotine
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
MERCK INDEX
M9674
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY Merck Index
NCI_THESAURUS
C77566
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
PUBCHEM
59227
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
RS_ITEM_NUM
1606060
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
RXCUI
616739
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY RxNorm
WIKIPEDIA
ROTIGOTINE
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
PRIMARY
Related Record Type Details Access References
EXCRETED UNCHANGED
Mediator Substance Details
none
URINE
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
TARGET -> AGONIST
none
Mediator Substance Details
none
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
TARGET -> AGONIST
none
Mediator Substance Details
none
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
BINDER->LIGAND
Mediator Substance Details
none
BINDING
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
TARGET -> AGONIST
none
Mediator Substance Details
none
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Related Record Type Details Access References
METABOLITE -> PARENT
none
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
METABOLITE -> PARENT
Mediator Substance Details
none
MINOR
URINE
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
METABOLITE -> PARENT
Mediator Substance Details
none
MAJOR
PLASMA; URINE
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
METABOLITE -> PARENT
Mediator Substance Details
none
sulfotransferases
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Related Record Type Details Access References
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
none
Mediator Substance Details
none
MINOR
below LOQ (300 dpm/ml)
URINE
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
IMPURITY -> PARENT
Mediator Substance Details
none
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Related Record Type Details Access References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Tue Aug 03 21:58:44 EDT 2021 , Edited by admin on Tue Aug 03 21:58:44 EDT 2021
Name Property Type Amount Referenced Substance Defining Parameters Access References
Volume of Distribution PHARMACOKINETIC
Tmax PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
Created Tue Aug 03 21:58:44 EDT 2021
Created By admin
Last Edited Tue Aug 03 21:58:44 EDT 2021
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File Access
1 https://www.clinicalkey.com/pharmacology/monograph/3114?sec=monphar CLINICAL PHARMACOLOGY
2 SRS CODE IMPORT SRS NOMEN Fri Apr 28 10:40:35 EDT 2017
3 MARTINDALE 2011 SRS NOMEN
4 DMD, OCTOBER 2009 VOL. 37 NO. 10 2055-2060 JOURNAL ARTICLE NOMEN
5 EP 01/2019:3014 EUROPEAN PHARMACOPEIA
6 WHO-DD SRS NOMEN
7 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
8 ROTIGOTINE [JAN] SRS_LOCATOR
9 USP-RS USPNF
10 ORANGE BOOK 2011 SRS NOMEN
11 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
12 STN STN (SCIFINDER)
13 USP DICTIONARY 2010 SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
14 EMA SRS NOMEN
15 NDF-RT SRS NOMEN
16 DMD, OCTOBER 2009 VOL. 37 NO. 10 2055-2060 JOURNAL ARTICLE NOMEN
17 EP 10.5 EP
18 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
19 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
20 ROTIGOTINE [WHO-DD] SRS_LOCATOR
21 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
22 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
23 INN Proposed List 83 INN_LIST PUBLIC_DOMAIN_RELEASE
24 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
25 clinicaltrials.gov SRS NOMEN
26 ep 01/2019:3014 EUROPEAN PHARMACOPEIA
27 USAN COUN 2003 USANCOUN NOMEN PUBLIC_DOMAIN_RELEASE
28 USP DICTIONARY 2011 SRS NOMEN
29 http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002380/human_med_001458. SRS NOMEN
30 ROTIGOTINE [EMA EPAR] SRS_LOCATOR
31 ROTIGOTINE [VANDF] SRS_LOCATOR
32 dump-public-2021-07-22_UPDATED.gsrs BATCH_IMPORT Tue Aug 03 21:58:43 EDT 2021
33 https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021829lbl.pdf NDA PUBLIC REVIEW PUBLIC_DOMAIN_RELEASE
34 WEBSITE WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
35 USP 10/2020 USPNF
36 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
37 ROTIGOTINE [MI] SRS_LOCATOR
38 http://www.accessdata.fda.gov/spl/data/cf5e27a6-ca06-40a3-a785-6c6360b3c6a6/cf5e27a6-ca06-40a3-a785-6c6360b3c6a6.xml WEBSITE NOMEN
39 ROTIGOTINE [INN] SRS_LOCATOR
40 SYSTEM
41 ROTIGOTINE [ORANGE BOOK] SRS_LOCATOR
42 ROTIGOTINE [USAN] SRS_LOCATOR
43 ROTIGOTINE [MART.] SRS_LOCATOR
44 KEGG 2011 SRS NOMEN
45 MERCK INDEX SRS NOMEN
46 USP DICTIONARY SRS NOMEN
47 SRS import [87T4T8BO2E] SRS NOMEN Fri Apr 28 10:40:35 EDT 2017
48 European Pharmacopoeia Online 9.8, Rotigotine Monograph EP PUBLIC_DOMAIN_RELEASE
49 EP 01/2019:3014 EUROPEAN PHARMACOPEIA
50 https://www.drugbank.ca/drugs/DB05271 WEBSITE

Version

Version Comments

Editor

Change Date

41
admin
Wed Aug 04 18:15:58 EDT 2021

Molecular Formula C19H25NOS
Molecular Weight 315.473
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED