{"created":1772548488715,"createdBy":"ADMIN","lastEdited":1772548488715,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"2c58c883-4d23-44db-81d7-22c21df65fbe","definitionType":"PRIMARY","definitionLevel":"COMPLETE","substanceClass":"chemical","status":"approved","version":"5","approvedBy":"FDA_SRS","approvalID":"N8OH05250C","structure":{"id":"7fa6298b-be4a-44ec-ae3d-533e6dda992c","created":1772548488716,"lastEdited":1772548488722,"deprecated":false,"digest":"997c73d3d0cd8b32cd1bf80d2b79120267d27bce","molfile":"\n  Marvin  01132106382D          \n\n 41 45  0  0  1  0            999 V2000\n    6.8644   -4.4343    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.2747   -3.7216    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.0794   -3.8927    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    8.6946   -3.3409    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    9.4809   -3.5937    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.0917   -3.0464    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0\n   10.8781   -3.2992    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   11.4889   -2.7474    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0\n   11.3177   -1.9381    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.5358   -1.6852    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.3648   -0.8760    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    9.9206   -2.2371    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   12.2752   -3.0002    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    8.1657   -4.7150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4162   -5.0494    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.2405   -5.8588    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.4587   -6.1117    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.2876   -6.9163    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.8982   -7.4729    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.6847   -7.2154    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.8558   -6.4107    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.8830   -5.1252    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.8830   -5.9502    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    9.5956   -6.3651    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.3129   -5.9502    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.3129   -5.1252    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    9.5956   -4.7150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   11.0256   -6.3651    0.0000 F   0  0  0  0  0  0  0  0  0  0  0  0\n    6.9401   -2.9676    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.1177   -2.8813    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    7.4232   -2.2999    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.0422   -4.5206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.7076   -5.2746    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    4.8852   -5.3609    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.3976   -4.6933    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.5798   -4.7796    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.2454   -5.5336    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.7284   -6.2013    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.5507   -6.1150    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.9565   -6.7618    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.5544   -3.8529    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  2  0  0  0  0\n  3  2  1  0  0  0  0\n  4  3  1  0  0  0  0\n  5  4  1  0  0  0  0\n  6  5  1  1  0  0  0\n  7  6  1  0  0  0  0\n  8  7  1  0  0  0  0\n  9  8  1  0  0  0  0\n 10  9  1  0  0  0  0\n 11 10  2  0  0  0  0\n 12 10  1  0  0  0  0\n  6 12  1  0  0  0  0\n  8 13  1  6  0  0  0\n 14  3  1  0  0  0  0\n 14 15  2  0  0  0  0\n 15  1  1  0  0  0  0\n 16 15  1  0  0  0  0\n 17 16  1  0  0  0  0\n 18 17  2  0  0  0  0\n 19 18  1  0  0  0  0\n 19 20  2  0  0  0  0\n 20 21  1  0  0  0  0\n 21 16  2  0  0  0  0\n 22 14  1  0  0  0  0\n 23 22  1  0  0  0  0\n 24 23  2  0  0  0  0\n 25 24  1  0  0  0  0\n 25 26  2  0  0  0  0\n 26 27  1  0  0  0  0\n 27 22  2  0  0  0  0\n 28 25  1  0  0  0  0\n 29  2  1  0  0  0  0\n 30 29  1  0  0  0  0\n 31 29  1  0  0  0  0\n 32  1  1  0  0  0  0\n 33 32  1  0  0  0  0\n 34 33  1  0  0  0  0\n 35 34  1  0  0  0  0\n 36 35  2  0  0  0  0\n 37 36  1  0  0  0  0\n 37 38  2  0  0  0  0\n 38 39  1  0  0  0  0\n 39 34  2  0  0  0  0\n 39 40  1  0  0  0  0\n 41 32  2  0  0  0  0\nM  END","smiles":"CC(C)c1c(c(-c2ccccc2)c(-c3ccc(cc3)F)n1CC[C@@H]4C[C@H](CC(=O)O4)O)C(=O)Nc5ccccc5O","formula":"C33H33FN2O5","opticalActivity":"UNSPECIFIED","atropisomerism":"No","stereoCenters":2,"definedStereo":2,"ezCenters":0,"charge":0,"mwt":556.6252,"count":1,"createdBy":"ADMIN","lastEditedBy":"ADMIN","stereochemistry":"ABSOLUTE","references":["ddbad785-27ef-42fe-b654-beae9e4c84c0","f76856f8-f38d-4d1e-9f2c-4680368aa63c"],"access":[],"hash":"MNECBMZJZFGTIK_JWQCQUIFSA_N","_inchiKey":"MNECBMZJZFGTIK-JWQCQUIFSA-N","_inchi":"InChI=1S/C33H33FN2O5/c1-20(2)31-30(33(40)35-26-10-6-7-11-27(26)38)29(21-8-4-3-5-9-21)32(22-12-14-23(34)15-13-22)36(31)17-16-25-18-24(37)19-28(39)41-25/h3-15,20,24-25,37-38H,16-19H2,1-2H3,(H,35,40)/t24-,25-/m1/s1"},"_name":"O-HYDROXYATORVASTATIN LACTONE","_approvalIDDisplay":"N8OH05250C","access":[],"_self":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)?view=full","_moieties":{"count":1,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/moieties"},"_names":{"count":7,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/names"},"_codes":{"count":4,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/codes"},"_properties":{"count":0,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/properties"},"_relationships":{"count":0,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/relationships"},"_references":{"count":10,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(2c58c883-4d23-44db-81d7-22c21df65fbe)/references"}}