{"created":1786327389080,"createdBy":"ADMIN","lastEdited":1786385214580,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"69a901de-d577-481e-bd9f-3d9d11dde852","definitionType":"PRIMARY","definitionLevel":"COMPLETE","substanceClass":"chemical","status":"approved","version":"52","approvedBy":"FDA_SRS","names":[{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"cbc5effc-e515-4730-9f4c-4e5ea6a51ac9","name":"Glutathione","stdName":"GLUTATHIONE","type":"of","domains":["cosmetic"],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"348e17f3-c7df-49e6-8a2c-d1b98343d99c","nameOrg":"INCI","references":[],"access":[]}],"preferred":false,"displayName":true,"references":["4db79d5b-c5be-4c1a-9b9d-ca6b89916fd8","1edbe6fa-1775-4089-b48f-199f3e8b4e92","0a906204-411c-40a0-bc65-5a5b06d15643","ef268f73-b4fb-4c6d-884b-16d304f03d07","61c07e95-abd4-4a9f-956d-94ec8971c2e5","64d58f57-01a9-4951-8b42-705f4e8585ea","779b4255-a1d9-4c7f-9c4e-8a9757f6615b","928987aa-1468-4523-840f-debb7a579f95","2cb97575-b404-4c0d-80a0-a8db5c7bf05e","02af7159-0a9f-4f60-af15-a6bf7fbdbcb7","08dd05fd-9391-4814-ae07-5343dc995efd","55102e72-9673-43af-9fe8-89d549ab8ae7","7aa2bba1-69d0-4d5b-aea3-3c5027735589","f6c4e7e8-087b-4e07-8ddc-c9d55656101c","051c3dfa-ed71-4e14-8036-984511f39fd2","8a7187fc-4afb-49a9-ba2b-44aac1b56e1d","69cc4bf8-d53a-406e-94b2-67f62af8d828"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"6e1d97f3-9184-5548-e6ce-f41e0d0740cb","name":"GLUTATHIONE [EP MONOGRAPH]","stdName":"GLUTATHIONE [EP MONOGRAPH]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["ee029844-deb7-fd28-6c9e-9832594f1739"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"72dcbada-c1f2-4005-a41e-9843172b84f7","name":"GLUTATHIONE [II]","stdName":"GLUTATHIONE [II]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["08dd05fd-9391-4814-ae07-5343dc995efd"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"33208fa2-fcf9-2217-7e0c-a9d97032ba5d","name":"GLUTATHIONE [JAN]","stdName":"GLUTATHIONE [JAN]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["67596cd7-cdc4-1bff-bc38-f624aba9a1e1"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9b625488-1f6b-447c-a644-dd33388f2dd0","name":"GLUTATHIONE [MART.]","stdName":"GLUTATHIONE [MART.]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["f6c4e7e8-087b-4e07-8ddc-c9d55656101c"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"535e6676-21df-4d41-8be8-d71ffd94580f","name":"GLUTATHIONE [MI]","stdName":"GLUTATHIONE [MI]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["2cb97575-b404-4c0d-80a0-a8db5c7bf05e","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f66629ac-a8e2-427c-8cae-98ed1b4a5f4c","name":"GLUTATHIONE [USP-RS]","stdName":"GLUTATHIONE [USP-RS]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["02af7159-0a9f-4f60-af15-a6bf7fbdbcb7","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"05332b72-e8bc-4dc4-91f7-53e129ae6010","name":"GLUTATHIONE [VANDF]","stdName":"GLUTATHIONE [VANDF]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["0a906204-411c-40a0-bc65-5a5b06d15643","69cc4bf8-d53a-406e-94b2-67f62af8d828"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"e50a3bd7-a0b2-05d1-7219-d52a8ce54b98","name":"Glutathione [WHO-DD]","stdName":"GLUTATHIONE [WHO-DD]","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["dcd3934c-9c65-49e7-b550-8d8bad7383cd"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"318f283b-95f2-4aa0-952c-901c4b81864e","name":"GLUTATHIONE, L-","stdName":"GLUTATHIONE, L-","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"45523bf6-cd81-4d72-9776-546df3971e6c","name":"GLUTHAM","stdName":"GLUTHAM","type":"bn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["9316ce41-67eb-46f3-88ef-4b261b38f75a","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"e9027c9c-3961-4c74-ada7-3fe634d30d00","name":"Glycine, L-γ-glutamyl-L-cysteinyl-","stdName":"GLYCINE, L-.GAMMA.-GLUTAMYL-L-CYSTEINYL-","type":"sys","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["f1d5a578-08db-48eb-9c02-1e0e07f01302","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"137e944e-33b7-4fa5-be34-167cfa93e34e","name":"ISETHION","stdName":"ISETHION","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["9316ce41-67eb-46f3-88ef-4b261b38f75a","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f7303dde-9a4e-4f3a-9afb-e43c637d51fc","name":"L-GLUTATHIONE REDUCED","stdName":"L-GLUTATHIONE REDUCED","type":"bn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["9316ce41-67eb-46f3-88ef-4b261b38f75a","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9cd85c68-d0b5-44be-ace5-d32553bba6f2","name":"L-γ-Glutamyl-L-cysteinylglycine","stdName":"L-.GAMMA.-GLUTAMYL-L-CYSTEINYLGLYCINE","type":"sys","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["08dd05fd-9391-4814-ae07-5343dc995efd"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"eaf21040-3aed-45c1-ba0d-642f3963eb0d","name":"NSC-400639","stdName":"NSC-400639","type":"cd","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["294152be-e998-4d62-890c-f3fdaefd4c2d"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"47835c9d-25f3-4a3d-be85-18fd83fc9774","name":"REDUCED L-GLUTATHIONE","stdName":"REDUCED L-GLUTATHIONE","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["01090fd6-e1db-4fd6-ac48-be8c424c1ae3","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"c213a87e-c8e3-4d11-a2fe-0b274db4fc9b","name":"TATHIONE","stdName":"TATHIONE","type":"cn","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["9316ce41-67eb-46f3-88ef-4b261b38f75a","0a906204-411c-40a0-bc65-5a5b06d15643"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"247afcfb-a195-437c-bc0f-c22b4d936e23","name":"γ-Glu-Cys-Gly","stdName":".GAMMA.-GLU-CYS-GLY","type":"sys","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["bb9711ce-7b61-41e2-b72b-ec90e7a22030"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"0adf3638-1b29-4a5c-90c9-3b4cbb93728d","name":"γ-Glutamylcysteinylglycine","stdName":".GAMMA.-GLUTAMYLCYSTEINYLGLYCINE","type":"sys","domains":[],"languages":["en"],"nameJurisdiction":[],"nameOrgs":[],"preferred":false,"displayName":false,"references":["294152be-e998-4d62-890c-f3fdaefd4c2d"],"access":[]}],"codes":[{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"1687c488-6cb3-d128-570f-617d2c8abe25","codeSystem":"RS_ITEM_NUM","code":"1294820","type":"PRIMARY","url":"https://store.usp.org/product/1294820","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"1ac9bf48-c93a-69d9-34a4-a5833bbf1bae","codeSystem":"LOINC","code":"57005-1","comments":"LOINC|ACTIVE|CHEM|Ser/Plas|Glutathione [Moles/volume] in Serum or Plasma","type":"PRIMARY","url":"https://loinc.org/57005-1/","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"1cb3e0c2-27bd-13a4-8410-135b7934b05c","codeSystem":"FDA ORPHAN DRUG","code":"303410","comments":"ORPHAN DRUG|Designated|Support of glutathione deficiency in individuals with inborn errors of metabolism of glutathione (IEMG)","type":"PRIMARY","url":"https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=303410","_isClassification":true,"references":[],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"264f19fb-ccf0-2eb2-809c-80c1b79c1984","codeSystem":"LOINC","code":"91685-8","comments":"LOINC|ACTIVE|CHEM|Bld|Glutathione [Mass/volume] in Blood","type":"PRIMARY","url":"https://loinc.org/91685-8/","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"2df1e5cb-1b27-ad56-858a-68997237b851","codeSystem":"DAILYMED","code":"GAN16C9B8O","type":"PRIMARY","url":"https://dailymed.nlm.nih.gov/dailymed/search.cfm?adv=1&query=GAN16C9B8O","_isClassification":false,"references":["8e50afb8-a12e-a77a-829d-3646e652903a"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"335fbcae-c547-a93a-2638-bd04c7da2b27","codeSystem":"CHEBI","code":"16856","type":"PRIMARY","url":"https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:16856","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"35b34848-7cd6-786b-1b19-31d7ef136deb","codeSystem":"DSLD","code":"1621 (Number of products:627)","comments":"Dietary Supplement Label Database|chemical|Glutathione","type":"PRIMARY","url":"https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=1621&item=Glutathione","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"378976b5-4fc3-4880-b7f3-071754d9c77f","codeSystem":"WIKIPEDIA","code":"GLUTATHIONE","type":"PRIMARY","url":"https://en.wikipedia.org/wiki/Glutathione","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"3a707419-fa64-b709-9a00-540419d81c36","codeSystem":"NSC","code":"400639","type":"PRIMARY","url":"https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=400639","_isClassification":false,"references":["15390996-1a10-b29b-3fb3-398903b04134"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"3d02d9fe-b868-46e8-99b7-4c64406f1272","codeSystem":"WHO-VATC","code":"QV03AB32","comments":"VATC|ALL OTHER THERAPEUTIC PRODUCTS|ALL OTHER THERAPEUTIC PRODUCTS|Antidotes|glutathione","type":"PRIMARY","url":"http://www.whocc.no/atcvet/atcvet_index/?code=QV03AB32&showdescription=yes","_isClassification":true,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"46fce9f9-881d-b1a2-56ce-211598951e0d","codeSystem":"CHEBI","code":"57925","type":"PRIMARY","url":"https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI:57925","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4bef3c9f-21af-c754-040a-f37a7fc2fa6b","codeSystem":"SMS_ID","code":"100000092913","type":"PRIMARY","_isClassification":false,"references":["054975c1-fe09-f996-d01a-20afb0e20b89"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"53441435-cc5e-62c6-dcf8-e59805aa1cf5","codeSystem":"FDA ORPHAN DRUG","code":"77493","comments":"ORPHAN DRUG|Designated|Treatment of AIDS-associated cachexia.","type":"PRIMARY","url":"https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=77493","_isClassification":true,"references":[],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"546cfada-23d7-484d-840e-64cdec4c7657","codeSystem":"CAS","code":"70-18-8","type":"PRIMARY","url":"https://commonchemistry.cas.org/detail?cas_rn=70-18-8","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254","743b14b0-1928-4a57-b977-d1d472491667"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"5682cb3c-4e8e-4f79-9c0a-c2da41b788f1","codeSystem":"NCI_THESAURUS","code":"C523","type":"PRIMARY","url":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C523","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"57f6d17b-d9ee-d166-ab08-3fcdd9fa437c","codeSystem":"LOINC","code":"16918-5","comments":"LOINC|ACTIVE|CHEM|Ser/Plas|Glutathione [Mass/volume] in Serum or Plasma","type":"PRIMARY","url":"https://loinc.org/16918-5/","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"5826c27d-f285-4cb9-92ab-1fee1c3aa213","codeSystem":"ChEMBL","code":"CHEMBL1543","type":"PRIMARY","url":"https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL1543","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"6400dbf0-eae8-49b0-9f82-f9719cbff7c5","codeSystem":"DRUG BANK","code":"DB00143","type":"PRIMARY","url":"http://www.drugbank.ca/drugs/DB00143","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"69e7e874-6ad4-1ae6-63f2-231ec4f3e29e","codeSystem":"LOINC","code":"65363-4","comments":"LOINC|ACTIVE|CHEM|Bld|Glutathione [Moles/volume] in Blood","type":"PRIMARY","url":"https://loinc.org/65363-4/","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"6c08cd12-f26d-ef73-6e61-b228a22946af","codeSystem":"FDA ORPHAN DRUG","code":"545816","comments":"ORPHAN DRUG|Designated|Treatment of lung dysfunction following lung transplant","type":"PRIMARY","url":"https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=545816","_isClassification":true,"references":[],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"7e5244a8-cc44-4942-87db-ef1ab5455511","codeSystem":"EVMPD","code":"SUB13990MIG","type":"PRIMARY","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"83c9c9cb-b193-4039-fded-08483cff3799","codeSystem":"NCI_THESAURUS","code":"C275","comments":"Pharmacologic Substance[C1909]|Protective Agent[C26170]|Antioxidant","type":"CONCEPT","url":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C275","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"8535997f-17ed-60ee-3a5f-ad637cb18d95","codeSystem":"FDA ORPHAN DRUG","code":"311910","comments":"ORPHAN DRUG|Designated|Treatment of glioma","type":"PRIMARY","url":"https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=311910","_isClassification":true,"references":[],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"87eebcfb-743d-42b2-9f43-69a1b8bfb094","codeSystem":"CFR","code":"21 CFR 862.1365","comments":"PART 862 -- CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES|Subpart B--Clinical Chemistry Test Systems|Sec. 862.1365 Glutathione test system.","type":"PRIMARY","url":"http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=862.1365","_isClassification":true,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"8a034fb4-7b49-48fb-8442-ee91af5464e3","codeSystem":"RXCUI","code":"4890","comments":"RxNorm","type":"PRIMARY","url":"https://rxnav.nlm.nih.gov/REST/rxcui/4890/allProperties.xml?prop=all","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"8fdb8aa6-3842-4c13-a7e4-77d85cc083c9","codeSystem":"PUBCHEM","code":"124886","type":"PRIMARY","url":"https://pubchem.ncbi.nlm.nih.gov/compound/124886","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"978ef56f-ec79-4295-5ff0-adbc1366b08c","codeSystem":"FDA ORPHAN DRUG","code":"519216","comments":"ORPHAN DRUG|Designated|Treatment of Dengue Virus infection.","type":"PRIMARY","url":"https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=519216","_isClassification":true,"references":[],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9b97089d-bdd7-3ded-6505-9b1ca91193e9","codeSystem":"EPA CompTox","code":"DTXSID6023101","type":"PRIMARY","url":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID6023101","_isClassification":false,"references":["62b32cb8-e244-9af0-d728-7b01bb0ae6b8"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9ebf9aa8-7dc5-4786-db74-67befce1df36","codeSystem":"GRAS Notification (GRN No.)","code":"244","type":"PRIMARY","url":"https://www.cfsanappsexternal.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=244","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"a3fc884b-3b7c-f2ed-8c29-d68a90374931","codeSystem":"GRAS Notification (GRN No.)","code":"293","type":"PRIMARY","url":"https://www.cfsanappsexternal.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=293","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"a901e12f-6665-a89f-8835-a3f1c9dd1725","codeSystem":"EU-Orphan Drug","code":"EU/3/06/361","comments":"EU ORPHAN DRUG|Withdrawn|Treatment of cystic fibrosis","type":"PRIMARY","url":"https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu306361","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"aa97599b-09fe-ea8e-b98e-79e647e703d0","codeSystem":"DRUG CENTRAL","code":"1312","type":"PRIMARY","url":"https://drugcentral.org/drugcard/1312","_isClassification":false,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"b2b1a915-e666-42fb-8339-fc6f81da9ae9","codeSystem":"MERCK INDEX","code":"m5781","comments":"Merck Index","type":"PRIMARY","url":"https://merckindex.rsc.org/monographs/m5781?q=authorize","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"b5876f10-53d9-04ff-c2c8-2d860dc939ba","codeSystem":"DSLD","code":"178 (Number of products:20)","comments":"Dietary Supplement Label Database|Amino Acid|L-Gluthathione","type":"PRIMARY","url":"https://dsld.od.nih.gov/dsld/rptIngredient.jsp?grpid=178&item=L-Gluthathione","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"bab243bb-53f5-4da0-92d5-096ba2a2d6b7","codeSystem":"WHO-ATC","code":"V03AB32","comments":"ATC|VARIOUS|ALL OTHER THERAPEUTIC PRODUCTS|ALL OTHER THERAPEUTIC PRODUCTS|Antidotes|glutathione","type":"PRIMARY","url":"http://www.whocc.no/atc_ddd_index/?code=V03AB32&showdescription=yes","_isClassification":true,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"bb7db64e-f972-479a-9804-11a239d618b2","codeSystem":"ECHA","code":"200-725-4","type":"PRIMARY","url":"https://chem.echa.europa.eu/100.000.660","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"bbda5fc3-cec1-aaa8-ade3-db81980647f1","codeSystem":"LOINC","code":"2383-8","comments":"LOINC|ACTIVE|CHEM|RBC|Glutathione [Mass/volume] in Red Blood Cells","type":"PRIMARY","url":"https://loinc.org/2383-8/","_isClassification":true,"references":["9e1f57b9-57d0-a3af-98e8-e0a2f5247103"],"access":[]},{"created":1786327389084,"createdBy":"ADMIN","lastEdited":1786327389084,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"c1f6124d-e945-4568-90e4-d1ab95571a9b","codeSystem":"FDA UNII","code":"GAN16C9B8O","type":"PRIMARY","_isClassification":false,"references":[],"access":[]},{"created":1786327389083,"createdBy":"ADMIN","lastEdited":1786327389083,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"c7589210-01ca-4955-b9ca-87971121577b","codeSystem":"MESH","code":"D005978","type":"PRIMARY","url":"http://www.ncbi.nlm.nih.gov/mesh/68005978","_isClassification":false,"references":["5aa97935-16c8-4c15-ad5a-cd98b06c0254"],"access":[]}],"modifications":{"created":1786327389082,"createdBy":"ADMIN","lastEdited":1786327389082,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"ab956eb1-4363-417e-bf53-57cf2c637fbd","agentModifications":[],"physicalModifications":[],"structuralModifications":[],"references":[],"access":[]},"notes":[],"properties":[],"relationships":[{"created":1786385146596,"createdBy":"ADMIN","lastEdited":1786385146596,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"53191052-6c1b-4d0c-9b85-439031c1131d","relatedSubstance":{"created":1786385146595,"createdBy":"ADMIN","lastEdited":1786385146595,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"3407d8b0-ec9e-4b02-aa2a-3fd80e6cc1f4","refPname":"MRP-3","refuuid":"fdfb9f00-e4c4-475f-bbe3-4d0efbc7e932","substanceClass":"reference","approvalID":"1YV0492L5Z","name":"MRP-3","linkingID":"1YV0492L5Z","references":[],"access":[]},"originatorUuid":"b953743a-14f9-4186-aec4-d0a36a557f55","type":"TRANSPORTER->SUBSTRATE","references":["791cbf6f-ce50-43cd-ae8d-5f1ecd8c4f40","9df5eb48-a298-4783-874d-02a79ad62528"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"5bd02c2a-b2a5-4128-9d02-a9035a7777e7","amount":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"e99f1e9f-c0c5-4288-9663-f0ea82b4b818","references":[],"access":[]},"relatedSubstance":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"5c5b4f26-eb20-4ef5-8c2c-55671b711edd","refPname":"Glutathione","refuuid":"69a901de-d577-481e-bd9f-3d9d11dde852","substanceClass":"reference","approvalID":"GAN16C9B8O","name":"Glutathione","linkingID":"GAN16C9B8O","references":[],"access":[]},"originatorUuid":"5bd02c2a-b2a5-4128-9d02-a9035a7777e7","type":"ACTIVE MOIETY","references":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"68484f68-4429-44d7-90d9-9c7f753b83cc","amount":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"d5c063cc-e847-4f5b-9c44-ecb6560c5064","references":[],"access":[]},"relatedSubstance":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f907c498-95bb-4ab3-9e9c-a0ab84702833","refPname":"2-Methylenequinuclidin-3-one","refuuid":"69021c8e-4e87-4153-9739-da29ef50bb99","approvalID":"YBL6TAE47S","name":"2-Methylenequinuclidin-3-one","linkingID":"YBL6TAE47S","references":[],"access":[]},"originatorUuid":"907185bd-baf1-4514-a563-95eae105fdd5","type":"SUBSTRATE->TARGET","references":["19773e2d-dd73-47a7-af7f-19dd97a69576"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"83a53b85-5cf5-4251-bca4-a669df6c176c","amount":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"adbcb2de-1232-43c5-a28f-982b7c0fd63a","references":[],"access":[]},"relatedSubstance":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f7354d8a-4290-4c21-8451-89a857bd02c6","refPname":"S-FORMYLGLUTATHIONE","refuuid":"e81477fc-0ced-40b3-a3f7-440a4543b8a8","approvalID":"3U89C4DNE8","name":"S-FORMYLGLUTATHIONE","linkingID":"3U89C4DNE8","references":[],"access":[]},"originatorUuid":"b49e391c-03bc-4a25-a62e-286b773d8f70","type":"DERIVATIVE->PARENT","references":["bb9711ce-7b61-41e2-b72b-ec90e7a22030"],"access":[]},{"created":1786384586821,"createdBy":"ADMIN","lastEdited":1786384586821,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"97359604-6562-495d-bd11-a87c2da986fa","amount":{"created":1786384586821,"createdBy":"ADMIN","lastEdited":1786384586821,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4830eb35-ab0c-4046-add2-b5dac5662c62","references":[],"access":[]},"relatedSubstance":{"created":1786384586821,"createdBy":"ADMIN","lastEdited":1786384586821,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"0aa85e7d-21e0-45a8-b16a-adf4c1cd8a0b","refPname":"MRP-1","refuuid":"a92ba84a-46dc-4e3f-80d1-e490da271998","substanceClass":"reference","approvalID":"Y49M64GZ4Q","name":"MRP-1","linkingID":"Y49M64GZ4Q","references":[],"access":[]},"originatorUuid":"21f50d82-2a94-46f1-8ed1-4481e3aca5dc","type":"TRANSPORTER->SUBSTRATE","references":["38c642d0-6e43-4cda-8802-2932eaa8e1dd","9ee01d12-75c3-4757-afa3-14b994a94f1c"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"ab5c8e7a-ec99-48d9-8685-23f6dd31a1b7","amount":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"233e603a-4421-4684-8a10-7b078605637b","references":[],"access":[]},"relatedSubstance":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"6cdc866b-f125-4145-a45d-222f0e45037c","refPname":"GLUTATHIONE SODIUM","refuuid":"5177e245-4b9f-4922-a375-67b2e25c4e17","substanceClass":"reference","approvalID":"H0X6UKX533","name":"GLUTATHIONE SODIUM","linkingID":"H0X6UKX533","references":[],"access":[]},"originatorUuid":"ab5c8e7a-ec99-48d9-8685-23f6dd31a1b7","type":"SALT/SOLVATE->PARENT","references":[],"access":[]},{"created":1786385214579,"createdBy":"ADMIN","lastEdited":1786385214579,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"e124bc4f-e5f7-4262-9e3a-332123b08588","relatedSubstance":{"created":1786385214579,"createdBy":"ADMIN","lastEdited":1786385214579,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4595c49b-020c-4b57-aed7-10c41c4aefa3","refPname":"MRP-2","refuuid":"b4997637-93fc-4a84-9c54-a054fde9cfaf","substanceClass":"reference","approvalID":"4AF605U6JN","name":"MRP-2","linkingID":"4AF605U6JN","references":[],"access":[]},"originatorUuid":"f044275b-f88d-4580-9c32-52fa191b87fd","type":"TRANSPORTER->SUBSTRATE","references":["43de21dd-f27a-4f21-acaa-7638484d1b7a","981df1e4-0ac4-4e5a-ac90-c4efc6000a43"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"ed966dc9-51a6-4257-a8ed-be1ce3d024e9","amount":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4e6c8a85-bfc2-4170-a6b8-b2403947d8e3","references":[],"access":[]},"comments":"Reacts with thiols leading to depletion and indirect oxidative damge.","relatedSubstance":{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4cb383ed-b377-4e8a-8cd1-d937986cc30a","refPname":"Nibrozetone","refuuid":"e6021fad-4b8d-4fc7-a4f1-7cb275548504","substanceClass":"reference","approvalID":"7RPW6SU9SC","name":"Nibrozetone","linkingID":"7RPW6SU9SC","references":[],"access":[]},"originatorUuid":"113a7c55-3606-4d93-b7f4-b9ec66c96f63","type":"INHIBITOR->TARGET","references":[],"access":[]}],"references":[{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"01090fd6-e1db-4fd6-ac48-be8c424c1ae3","citation":"ORPHAN","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"02af7159-0a9f-4f60-af15-a6bf7fbdbcb7","citation":"USP/NF","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"051c3dfa-ed71-4e14-8036-984511f39fd2","citation":"GLUTATHIONE [MART.]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"054975c1-fe09-f996-d01a-20afb0e20b89","citation":"EU-SRS","docType":"EMA LIST","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"0896a3a3-a7e9-495d-a7c5-401a481a3c46","citation":"USP Dictionary 2010","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"08dd05fd-9391-4814-ae07-5343dc995efd","citation":"USP DICTIONARY 2010","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN","PUBLIC_DOMAIN_RELEASE","AUTO_SELECTED"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"0a906204-411c-40a0-bc65-5a5b06d15643","citation":"MERCK INDEX","docType":"MERCK INDEX","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"15390996-1a10-b29b-3fb3-398903b04134","citation":"NCI","docType":"NCI DRUG DICTIONARY","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"19773e2d-dd73-47a7-af7f-19dd97a69576","citation":"Bykov VJ, Zhang Q, Zhang M, Ceder S, Abrahmsen L, Wiman KG. Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy. Front Oncol. 2016 Feb 3;6:21. doi: 10.3389/fonc.2016.00021. PMID: 26870698; PMCID: PMC4737887.","docType":"JA","publicDomain":true,"tags":["PUBLIC_DOMAIN_RELEASE"],"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737887/","access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"1edbe6fa-1775-4089-b48f-199f3e8b4e92","citation":"GLUTATHIONE [WHO-DD]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"294152be-e998-4d62-890c-f3fdaefd4c2d","citation":"STN 2007","docType":"STN (SCIFINDER)","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"2cb97575-b404-4c0d-80a0-a8db5c7bf05e","citation":"MERCK INDEX","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"325caf7b-91f6-457e-9861-85799603a732","citation":"SRS import [GAN16C9B8O]","docType":"FDA_SRS","documentDate":1493404095000,"publicDomain":true,"tags":["NOMEN"],"url":"http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=GAN16C9B8O","access":[]},{"created":1786384586820,"createdBy":"ADMIN","lastEdited":1786384586820,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"38c642d0-6e43-4cda-8802-2932eaa8e1dd","citation":"Generated from relationship on:'MRP-1'","docType":"SYSTEM","publicDomain":false,"tags":[],"access":[]},{"created":1786385214579,"createdBy":"ADMIN","lastEdited":1786385214579,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"43de21dd-f27a-4f21-acaa-7638484d1b7a","citation":"Generated from relationship on:'MRP-2'","docType":"SYSTEM","publicDomain":false,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"4db79d5b-c5be-4c1a-9b9d-ca6b89916fd8","citation":"GLUTATHIONE [MI]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"55102e72-9673-43af-9fe8-89d549ab8ae7","citation":"WHO-DD","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"5aa97935-16c8-4c15-ad5a-cd98b06c0254","citation":"SRS CODE IMPORT","docType":"FDA_SRS","documentDate":1493404095000,"publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"61c07e95-abd4-4a9f-956d-94ec8971c2e5","citation":"PCPC","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"62b32cb8-e244-9af0-d728-7b01bb0ae6b8","citation":"WEBSITE","docType":"WEBSITE","publicDomain":true,"tags":["NOMEN","PUBLIC_DOMAIN_RELEASE"],"url":"https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=70-18-8","access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"64d58f57-01a9-4951-8b42-705f4e8585ea","citation":"GLUTATHIONE [INCI]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"67596cd7-cdc4-1bff-bc38-f624aba9a1e1","citation":"JAN","docType":"JAN","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"69cc4bf8-d53a-406e-94b2-67f62af8d828","citation":"NDF-RT","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"743b14b0-1928-4a57-b977-d1d472491667","citation":"STN","docType":"STN (SCIFINDER)","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"779b4255-a1d9-4c7f-9c4e-8a9757f6615b","citation":"GLUTATHIONE [USP-RS]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786385146595,"createdBy":"ADMIN","lastEdited":1786385146595,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"791cbf6f-ce50-43cd-ae8d-5f1ecd8c4f40","citation":"Generated from relationship on:'MRP-3'","docType":"SYSTEM","publicDomain":false,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"7aa2bba1-69d0-4d5b-aea3-3c5027735589","citation":"EP 7.2","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"8a7187fc-4afb-49a9-ba2b-44aac1b56e1d","citation":"GLUTATHIONE [II]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"8e50afb8-a12e-a77a-829d-3646e652903a","citation":"DailyMed","docType":"DAILYMED","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"928987aa-1468-4523-840f-debb7a579f95","citation":"GLUTATHIONE [EP]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9316ce41-67eb-46f3-88ef-4b261b38f75a","citation":"PCPC-DB","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786385214579,"createdBy":"ADMIN","lastEdited":1786385214579,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"981df1e4-0ac4-4e5a-ac90-c4efc6000a43","citation":"DRUG METABOLISM HANDBOOK, ED. A.F. NASSER, 2009, PG:91","docType":"BOOK","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786385146595,"createdBy":"ADMIN","lastEdited":1786385146595,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9df5eb48-a298-4783-874d-02a79ad62528","citation":"DRUG METABOLISM HANDBOOK, ED. A.F. NASSER, 2009, PG:91","docType":"BOOK","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9e1f57b9-57d0-a3af-98e8-e0a2f5247103","docType":"SYSTEM","publicDomain":true,"tags":[],"access":[]},{"created":1786384586820,"createdBy":"ADMIN","lastEdited":1786384586820,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"9ee01d12-75c3-4757-afa3-14b994a94f1c","citation":"DRUG METABOLISM HANDBOOK, ED. A.F. NASSER, 2009, PG:91","docType":"BOOK","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"bb9711ce-7b61-41e2-b72b-ec90e7a22030","citation":"STN","docType":"STN (SCIFINDER)","publicDomain":true,"tags":["PUBLIC_DOMAIN_RELEASE"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"cf0af4dd-66ab-4c7a-aac0-c69bea28f2be","citation":"Ross, David. \"Glutathione, free radicals and chemotherapeutic agents: mechanisms of free-radical induced toxicity and glutathione-dependent protection.\" Pharmacology & therapeutics 37.2 (1988): 231-249.","docType":"JA","publicDomain":true,"tags":[],"url":"https://www.sciencedirect.com/science/article/pii/0163725888900277","access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"dcd3934c-9c65-49e7-b550-8d8bad7383cd","citation":"WHO-DD","docType":"WHO DRUG DICTIONARY","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"ee029844-deb7-fd28-6c9e-9832594f1739","citation":"EP 10.5","docType":"EP","publicDomain":true,"tags":[],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"ef268f73-b4fb-4c6d-884b-16d304f03d07","citation":"GLUTATHIONE [VANDF]","docType":"SRS_LOCATOR","publicDomain":true,"tags":[],"access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f1d5a578-08db-48eb-9c02-1e0e07f01302","citation":"STN","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]},{"created":1786327389086,"createdBy":"ADMIN","lastEdited":1786327389086,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f2db3e65-b8de-476a-82f9-f5729ca07f70","citation":"Ross, David. \"Glutathione, free radicals and chemotherapeutic agents: mechanisms of free-radical induced toxicity and glutathione-dependent protection.\" Pharmacology & therapeutics 37.2 (1988): 231-249.","docType":"JA","publicDomain":true,"tags":[],"url":"https://www.sciencedirect.com/science/article/pii/0163725888900277","access":[]},{"created":1786327389085,"createdBy":"ADMIN","lastEdited":1786327389085,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"f6c4e7e8-087b-4e07-8ddc-c9d55656101c","citation":"MARTINDALE 2011","docType":"FDA_SRS","publicDomain":true,"tags":["NOMEN"],"access":[]}],"approvalID":"GAN16C9B8O","tags":[],"structure":{"id":"2b5e446c-921d-4a2d-9b58-87199ab2ae7d","created":1786327389082,"lastEdited":1786327389089,"deprecated":false,"digest":"59647b415debeb9fc1b784404fe3367a09d17a6a","molfile":"\n  Marvin  01132102212D          \n\n 20 19  0  0  1  0            999 V2000\n    7.6470   -5.3530    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n    8.3647   -4.9462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    9.0876   -5.3530    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    9.8001   -4.9462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.5179   -5.3530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.5179   -6.1744    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   11.2330   -4.9462    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    8.3725   -4.1171    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.9552   -4.9696    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    6.2349   -5.3764    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.2349   -6.2055    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    5.5276   -4.9851    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.8176   -5.3997    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    4.0818   -5.0084    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0\n    4.0818   -4.1949    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.3512   -3.7958    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.7865   -3.7725    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    3.3822   -5.4308    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    7.6470   -6.1821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.3881   -6.7029    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0\n  2  1  1  0  0  0  0\n  3  2  1  0  0  0  0\n  4  3  1  0  0  0  0\n  5  4  1  0  0  0  0\n  6  5  2  0  0  0  0\n  7  5  1  0  0  0  0\n  8  2  2  0  0  0  0\n  9  1  1  0  0  0  0\n 10  9  1  0  0  0  0\n 11 10  2  0  0  0  0\n 12 10  1  0  0  0  0\n 13 12  1  0  0  0  0\n 14 13  1  0  0  0  0\n 15 14  1  0  0  0  0\n 16 15  2  0  0  0  0\n 17 15  1  0  0  0  0\n 14 18  1  6  0  0  0\n  1 19  1  6  0  0  0\n 20 19  1  0  0  0  0\nM  END","smiles":"C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N","formula":"C10H17N3O6S","opticalActivity":"UNSPECIFIED","atropisomerism":"No","stereoCenters":2,"definedStereo":2,"ezCenters":0,"charge":0,"mwt":307.325,"count":1,"createdBy":"ADMIN","lastEditedBy":"ADMIN","stereochemistry":"ABSOLUTE","access":[],"references":["325caf7b-91f6-457e-9861-85799603a732","0896a3a3-a7e9-495d-a7c5-401a481a3c46"],"_inchiKey":"RWSXRVCMGQZWBV-WDSKDSINSA-N","_inchi":"InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1","hash":"RWSXRVCMGQZWBV_WDSKDSINSA_N"},"moieties":[{"created":1786327389087,"createdBy":"ADMIN","lastEdited":1786327389089,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"a15b41db-2be8-4952-a1a1-f646e52fc12a","id":"a15b41db-2be8-4952-a1a1-f646e52fc12a","digest":"57e5e4f1b859a3c7bb451f49c0078f3049554faf","molfile":"\n  Marvin  01132108232D          \n\n 20 19  0  0  1  0            999 V2000\n    4.0818   -5.0084    0.0000 C   0  0  1  0  0  0  0  0  0  2  0  0\n    3.3822   -5.4308    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    4.8176   -5.3997    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    5.5276   -4.9851    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.2349   -5.3764    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    6.2349   -6.2055    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    6.9552   -4.9696    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    7.6470   -5.3530    0.0000 C   0  0  1  0  0  0  0  0  0  1  0  0\n    7.6470   -6.1821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.3881   -6.7029    0.0000 S   0  0  0  0  0  0  0  0  0  0  0  0\n    8.3647   -4.9462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    8.3725   -4.1171    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    9.0876   -5.3530    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n    9.8001   -4.9462    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.5179   -5.3530    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   10.5179   -6.1744    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   11.2330   -4.9462    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.0818   -4.1949    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n    3.3512   -3.7958    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n    4.7865   -3.7725    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  6  0  0  0\n  1  3  1  0  0  0  0\n  1 18  1  0  0  0  0\n  3  4  1  0  0  0  0\n  4  5  1  0  0  0  0\n  6  5  2  0  0  0  0\n  5  7  1  0  0  0  0\n  8  7  1  6  0  0  0\n  8  9  1  0  0  0  0\n  8 11  1  0  0  0  0\n 10  9  1  0  0  0  0\n 12 11  2  0  0  0  0\n 13 11  1  0  0  0  0\n 14 13  1  0  0  0  0\n 15 14  1  0  0  0  0\n 16 15  1  0  0  0  0\n 17 15  2  0  0  0  0\n 19 18  1  0  0  0  0\n 20 18  2  0  0  0  0\nM  END","smiles":"C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N","formula":"C10H17N3O6S","opticalActivity":"UNSPECIFIED","atropisomerism":"No","stereoCenters":2,"definedStereo":2,"ezCenters":0,"charge":0,"mwt":307.325,"count":1,"stereochemistry":"ABSOLUTE","access":[],"references":[],"_inchiKey":"RWSXRVCMGQZWBV-WDSKDSINSA-N","_inchi":"InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1","hash":"RWSXRVCMGQZWBV_WDSKDSINSA_N","countAmount":{"created":1786327389087,"createdBy":"ADMIN","lastEdited":1786327389087,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"072640f2-b48b-487d-a698-1b82e390c2c2","type":"MOL RATIO","average":1.0,"units":"MOL RATIO","references":[],"access":[]}}],"_name":"Glutathione","_approvalIDDisplay":"GAN16C9B8O","access":[],"_self":"https://gsrs.ncats.nih.gov/api/v1/substances(69a901de-d577-481e-bd9f-3d9d11dde852)?view=full"}