{"created":1786315579847,"createdBy":"ADMIN","lastEdited":1786315579847,"lastEditedBy":"ADMIN","deprecated":false,"uuid":"c1f07000-73a8-4f92-b258-f5743f576bc7","definitionType":"PRIMARY","definitionLevel":"COMPLETE","substanceClass":"chemical","status":"approved","version":"21","approvedBy":"FDA_SRS","approvalID":"13U86G7YSP","structure":{"id":"fcd2acc9-b970-4cea-8353-31d10676cf4c","created":1786315579849,"lastEdited":1786315579858,"deprecated":false,"digest":"93a2acb34c2070fece63cf721de722ea2e9584ff","molfile":"\n   JSDraw210212517582D\n\n 93 97  0  0  1  0              0 V2000\n   64.7462   -7.7234    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   64.4448   -9.2540    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   62.9685   -9.7583    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   62.6672  -11.2889    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   61.1910  -11.7932    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   63.8420  -12.3152    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   65.3694  -11.9720    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   66.1695  -13.3110    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   65.1383  -14.4845    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   63.7072  -13.8737    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   62.3697  -14.6765    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   61.0057  -13.9196    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   62.3961  -16.2363    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   63.7601  -16.9932    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   65.0977  -16.1905    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   66.4617  -16.9474    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   67.7992  -16.1446    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   69.1633  -16.9016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   69.1897  -18.4613    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   70.5008  -16.0988    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   61.0586  -17.0391    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   59.6946  -16.2821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   59.6681  -14.7223    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   58.3571  -17.0849    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   58.3835  -18.6447    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   59.7475  -19.4016    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   59.7739  -20.9613    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   61.0850  -18.5988    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   56.9931  -16.3279    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   55.6555  -17.1307    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   55.6820  -18.6904    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   54.2915  -16.3738    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   54.2650  -14.8140    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   52.9010  -14.0571    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   52.8746  -12.4974    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   54.4343  -12.4709    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   52.8481  -10.9376    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   51.3148  -12.5239    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   52.9540  -17.1766    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   51.5899  -16.4196    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   51.5635  -14.8599    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   50.2524  -17.2224    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   50.2788  -18.7821    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   51.6429  -19.5391    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   51.6616  -21.0990    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   52.9917  -21.8630    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   54.3862  -21.0662    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   54.3674  -19.5063    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   52.9542  -18.7433    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   55.7401  -21.8410    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   48.8884  -16.4655    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   47.5508  -17.2682    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   47.5773  -18.8280    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   46.1868  -16.5113    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   46.1604  -14.9515    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   44.7964  -14.1946    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   44.8493  -17.3141    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   43.4852  -16.5571    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   43.4588  -14.9973    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   42.1477  -17.3599    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   40.7838  -16.6029    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   40.7572  -15.0431    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   42.0039  -14.1122    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   41.5024  -12.6393    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   39.9372  -12.6658    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   38.8768  -11.5206    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   37.3515  -11.8751    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   36.8994  -13.3683    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   37.9630  -14.5036    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   39.4853  -14.1589    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   42.1741  -18.9196    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   40.8366  -19.7225    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   39.4726  -18.9655    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   40.8631  -21.2822    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   42.2271  -22.0391    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   42.2536  -23.5988    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   41.0067  -24.5413    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   41.5145  -26.0109    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   43.0722  -25.9806    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   43.5210  -24.4909    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   39.5255  -22.0850    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   38.1615  -21.3280    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   38.1350  -19.7683    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   36.8240  -22.1308    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   35.3873  -21.5173    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   34.3647  -22.6953    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   35.1742  -24.0314    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   34.5676  -25.4686    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   36.6902  -23.6810    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0\n   78.3183  -18.5480    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   79.6693  -17.7680    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0\n   79.6693  -16.2080    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n   81.0203  -18.5480    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0\n  1  2  1  0  0  0  0\n  2  3  1  0  0  0  0\n  3  4  1  0  0  0  0\n  4  5  2  0  0  0  0\n  6  4  1  6  0  0  0\n  6  7  1  0  0  0  0\n  7  8  1  0  0  0  0\n  8  9  1  0  0  0  0\n  9 10  1  0  0  0  0\n  6 10  1  0  0  0  0\n 10 11  1  0  0  0  0\n 11 12  2  0  0  0  0\n 11 13  1  0  0  0  0\n 13 14  1  0  0  0  0\n 14 15  1  0  0  0  0\n 15 16  1  0  0  0  0\n 16 17  1  0  0  0  0\n 17 18  1  0  0  0  0\n 18 19  2  0  0  0  0\n 18 20  1  0  0  0  0\n 13 21  1  6  0  0  0\n 21 22  1  0  0  0  0\n 22 23  2  0  0  0  0\n 22 24  1  0  0  0  0\n 24 25  1  0  0  0  0\n 25 26  1  0  0  0  0\n 26 27  1  0  0  0  0\n 26 28  1  0  0  0  0\n 24 29  1  6  0  0  0\n 29 30  1  0  0  0  0\n 30 31  2  0  0  0  0\n 30 32  1  0  0  0  0\n 32 33  1  0  0  0  0\n 33 34  1  0  0  0  0\n 34 35  1  0  0  0  0\n 35 36  1  0  0  0  0\n 35 37  1  0  0  0  0\n 35 38  1  0  0  0  0\n 32 39  1  6  0  0  0\n 39 40  1  0  0  0  0\n 40 41  2  0  0  0  0\n 40 42  1  0  0  0  0\n 42 43  1  0  0  0  0\n 43 44  1  0  0  0  0\n 44 45  2  0  0  0  0\n 45 46  1  0  0  0  0\n 46 47  2  0  0  0  0\n 47 48  1  0  0  0  0\n 48 49  2  0  0  0  0\n 44 49  1  0  0  0  0\n 47 50  1  0  0  0  0\n 42 51  1  6  0  0  0\n 51 52  1  0  0  0  0\n 52 53  2  0  0  0  0\n 52 54  1  0  0  0  0\n 54 55  1  0  0  0  0\n 55 56  1  0  0  0  0\n 54 57  1  1  0  0  0\n 57 58  1  0  0  0  0\n 58 59  2  0  0  0  0\n 58 60  1  0  0  0  0\n 60 61  1  0  0  0  0\n 61 62  1  0  0  0  0\n 62 63  2  0  0  0  0\n 63 64  1  0  0  0  0\n 64 65  1  0  0  0  0\n 65 66  2  0  0  0  0\n 66 67  1  0  0  0  0\n 67 68  2  0  0  0  0\n 68 69  1  0  0  0  0\n 69 70  2  0  0  0  0\n 62 70  1  0  0  0  0\n 65 70  1  0  0  0  0\n 60 71  1  1  0  0  0\n 71 72  1  0  0  0  0\n 72 73  2  0  0  0  0\n 72 74  1  0  0  0  0\n 74 75  1  0  0  0  0\n 75 76  1  0  0  0  0\n 76 77  2  0  0  0  0\n 77 78  1  0  0  0  0\n 78 79  1  0  0  0  0\n 79 80  2  0  0  0  0\n 76 80  1  0  0  0  0\n 74 81  1  6  0  0  0\n 81 82  1  0  0  0  0\n 82 83  2  0  0  0  0\n 84 82  1  1  0  0  0\n 84 85  1  0  0  0  0\n 85 86  1  0  0  0  0\n 86 87  1  0  0  0  0\n 87 88  2  0  0  0  0\n 87 89  1  0  0  0  0\n 84 89  1  0  0  0  0\n 90 91  1  0  0  0  0\n 91 92  2  0  0  0  0\n 91 93  1  0  0  0  0\nM  END","smiles":"CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O","formula":"C60H86N16O13.C2H4O2","opticalActivity":"UNSPECIFIED","atropisomerism":"No","stereoCenters":9,"definedStereo":9,"ezCenters":0,"charge":0,"mwt":1299.4786,"count":1,"createdBy":"ADMIN","lastEditedBy":"ADMIN","stereochemistry":"ABSOLUTE","access":[],"references":["f4505442-798c-4f29-8c0f-17a5f89f0bde","2171c2e4-d72d-4b7a-89b9-b37ee572e8c4"],"_inchiKey":"PYMDEDHDQYLBRT-DRIHCAFSSA-N","_inchi":"InChI=1S/C60H86N16O13.C2H4O2/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40;1-2(3)4/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65);1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47+,48-;/m0./s1","hash":"PYMDEDHDQYLBRT_DRIHCAFSSA_N"},"_name":"Buserelin Acetate","_approvalIDDisplay":"13U86G7YSP","access":[],"_self":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)?view=full","_moieties":{"count":2,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/moieties"},"_names":{"count":11,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/names"},"_codes":{"count":13,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/codes"},"_modifications":{"count":0,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/modifications"},"_properties":{"count":0,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/properties"},"_relationships":{"count":4,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/relationships"},"_references":{"count":25,"url":"https://gsrs.ncats.nih.gov/api/v1/substances(c1f07000-73a8-4f92-b258-f5743f576bc7)/references"}}